PATH-55. MUTATIONS OF H3.3 AND H3.1 IN A LARGE COHORT OF GLIOMAS

Mutations in the histone genes H3.3 and H3.1 are driver events in pediatric and adult gliomas and carry diagnostic and prognostic importance for tumors originating from midline structures. Patients with tumors affected by these mutations are difficult to treat. We surveyed a large cohort of gliomas...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Sumrall, Ashley, Mittal, Sandeep, Phuphanich, Surasak, Heimberger, Amy, Eschbacher, Jenny, Korn, Michael, Gatalica, Zoran, Pandey, Manjari, Xiu, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Molecular Pathology and Classification - Adult and Pediatric
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847206/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.650
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