RARE-22. FREQUENT HIGH TUMOR MUTATIONAL BURDEN (TMB) AND PD-L1 EXPRESSION IN PRIMARY CNS LYMPHOMA (PCNSL)

BACKGROUND: PD-1 and PD-L1 expression has not been well-described in PCNSL. In one report of 20 PCNSL tumors, PD-1 and PD-L1 expression on tumor cells (TC), tumor-infiltrating lymphocytes (TIL), or tumor-associated macrophages (TAM) was seen in 90% (Clin Neuropathol 2014;PMID:24359606). Another repo...

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Publicado no:Neuro Oncol
Main Authors: Sumrall, Ashley, Phuphanich, Surasak, Spetzler, David, Gatalica, Zoran, Xiu, Joanne, Provenzano, Aaron, J. Brenner, Andrew, Subramaniam, Deepa, Pandey, Majari, Heimberger, Amy, Kesari, Santosh, Michael Korn, W, Mittal, Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217688/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.996
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