Profiling plasma extracellular vesicle by pluronic block-copolymer based enrichment method unveils features associated with breast cancer aggression, metastasis and invasion

por Zhong, Zhenyu, Rosenow, Matthew, Xiao, Nick, Spetzler, David
Publicado en J Extracell Vesicles (2018)

Direct observation of stepped proteolipid ring rotation in E. coli F(o)F(1)-ATP synthase

por Ishmukhametov, Robert, Hornung, Tassilo, Spetzler, David, Frasch, Wayne D
Publicado 2010

Microsatellite instability status determined by next‐generation sequencing and compared with PD‐L1 and tumor mutational burden in 11,348 patients

por Vanderwalde, Ari, Spetzler, David, Xiao, Nianqing, Gatalica, Zoran, Marshall, John
Publicado en Cancer Med (2018)

KIAA0100 Modulates Cancer Cell Aggression Behavior of MDA-MB-231 through Microtubule and Heat Shock Proteins

por Zhong, Zhenyu, Pannu, Vaishali, Rosenow, Matthew, Stark, Adam, Spetzler, David
Publicado en Cancers (Basel) (2018)

Determination of torque generation from the power stroke of Escherichia coli F(1)-ATPase

por Hornung, Tassilo, Ishmukhametov, Robert, Spetzler, David, Martin, James, Frasch, Wayne D.
Publicado 2008

Microsecond Resolution of Single-Molecule Rotation Catalyzed by Molecular Motors

por Hornung, Tassilo, Martin, James, Spetzler, David, Ishmukhametov, Robert, Frasch, Wayne D.
Publicado en Methods Mol Biol (2011)

Response to “The need for validation of MI GPSai in patients with CUP: Comment on: “Machine learning analysis using 77,044 genomic and transcriptomic profiles to accurately predict...

por Abraham, Jim, Nabhan, Chadi, Oberley, Matthew, Korn, Wolfgang Michael, Spetzler, David
Publicado en Transl Oncol (2021)

Microsecond Time Scale Rotation Measurements of Single F(1)-ATPase Molecules()

por Spetzler, David, York, Justin, Daniel, Douglas, Fromme, Raimund, Lowry, David, Frasch, Wayne
Publicado en Biochemistry (2006)

Elastic coupling power stroke mechanism of the F(1)-ATPase molecular motor

por Martin, James L., Ishmukhametov, Robert, Spetzler, David, Hornung, Tassilo, Frasch, Wayne D.
Publicado en Proc Natl Acad Sci U S A (2018)

Single Molecule Measurements of F(1)-ATPase Reveal an Interdependence between the Power Stroke and the Dwell Duration

por Spetzler, David, Ishmukhametov, Robert, Hornung, Tassilo, Day, Lixia Jin, Martin, James, Frasch, Wayne D.
Publicado 2009

Genetic and immune profiling for potential therapeutic targets in adult human craniopharyngioma

por Kassab, Cynthia, Zamler, Daniel, Kamiya-Matsuoka, Carlos, Gatalica, Zoran, Xiu, Joanne, Spetzler, David, Heimberger, Amy B.
Publicado en Clin Oncol Res (2019)

Population bias in somatic measurement of microsatellite instability status

por Saul, Michelle, Poorman, Kelsey, Tae, Hongseok, Vanderwalde, Ari, Stafford, Phillip, Spetzler, David, Korn, Wolfgang M., Gatalica, Zoran, Swensen, Jeff
Publicado en Cancer Med (2020)

Ependymomas overexpress chemoresistance and DNA repair-related proteins

por Ferguson, Sherise D., Zhou, Shouhao, Xiu, Joanne, Hashimoto, Yuuri, Sanai, Nader, Kim, Lyndon, Kesari, Santosh, de Groot, John, Spetzler, David, Heimberger, Amy B.
Publicado en Oncotarget (2017)

Impact of molecular profiling on overall survival of patients with advanced ovarian cancer

por Herzog, Thomas J., Spetzler, David, Xiao, Nick, Burnett, Ken, Maney, Todd, Voss, Andreas, Reddy, Sandeep, Burger, Robert, Krivak, Thomas, Powell, Matthew, Friedlander, Michael, McGuire, William
Publicado en Oncotarget (2016)

Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy

por Hodges, Tiffany R., Ott, Martina, Xiu, Joanne, Gatalica, Zoran, Swensen, Jeff, Zhou, Shouhao, Huse, Jason T., de Groot, John, Li, Shulin, Overwijk, Willem W., Spetzler, David, Heimberger, Amy B.
Publicado en Neuro Oncol (2017)

Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas

por Ferguson, Sherise D, Zhou, Shouhao, Huse, Jason T, de Groot, John F, Xiu, Joanne, Subramaniam, Deepa S, Mehta, Shwetal, Gatalica, Zoran, Swensen, Jeffrey, Sanai, Nader, Spetzler, David, Heimberger, Amy B
Publicado en J Neuropathol Exp Neurol (2018)

RARE-22. FREQUENT HIGH TUMOR MUTATIONAL BURDEN (TMB) AND PD-L1 EXPRESSION IN PRIMARY CNS LYMPHOMA (PCNSL)

por Sumrall, Ashley, Phuphanich, Surasak, Spetzler, David, Gatalica, Zoran, Xiu, Joanne, Provenzano, Aaron, J. Brenner, Andrew, Subramaniam, Deepa, Pandey, Majari, Heimberger, Amy, Kesari, Santosh, Michael Korn, W, Mittal, Sandeep
Publicado en Neuro Oncol (2018)

Pan-cancer analysis of RNA expression of ANGIOTENSIN-I-CONVERTING ENZYME 2 reveals high variability and possible impact on COVID-19 clinical outcomes

por Elliott, Andrew, Saul, Michelle, Zeng, Jia, Marshall, John L., Kim, Edward S., Nagasaka, Misako, Lenz, Heinz-Josef, Schwartzberg, Lee, Spetzler, David, Abraham, Jim, Xiu, Joanne, Stafford, Phillip, Michael Korn, W.
Publicado en Sci Rep (2021)

Rethinking medulloblastoma from a targeted therapeutics perspective

por Hashimoto, Yuuri, Penas-Prado, Marta, Zhou, Shouhao, Wei, Jun, Khatua, Soumen, Hodges, Tiffany R., Sanai, Nader, Xiu, Joanne, Gatalica, Zoran, Kim, Lyndon, Kesari, Santosh, Rao, Ganesh, Spetzler, David, Heimberger, Amy
Publicado en J Neurooncol (2018)

Primary CNS lymphoma commonly expresses immune response biomarkers

por Ou, Alexander, Sumrall, Ashley, Phuphanich, Surasak, Spetzler, David, Gatalica, Zoran, Xiu, Joanne, Michelhaugh, Sharon, Brenner, Andrew, Pandey, Manjari, Kesari, Santosh, Korn, W Michael, Mittal, Sandeep, Westin, Jason, Heimberger, Amy B
Publicado en Neurooncol Adv (2020)