Ependymomas overexpress chemoresistance and DNA repair-related proteins

BACKGROUND: After surgery and radiation, treatment options for ependymoma are few making recurrence a challenging issue. Specifically, the efficacy of chemotherapy at recurrence is limited. We performed molecular profiling on a cohort of ependymoma cases in order to uncover therapeutic targets and t...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Ferguson, Sherise D., Zhou, Shouhao, Xiu, Joanne, Hashimoto, Yuuri, Sanai, Nader, Kim, Lyndon, Kesari, Santosh, de Groot, John, Spetzler, David, Heimberger, Amy B.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814261/
https://ncbi.nlm.nih.gov/pubmed/29487694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23288
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