Immune checkpoint blockade as a potential therapeutic target: surveying CNS malignancies

BACKGROUND: Expression of programmed cell death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) across glioma grades is undocumented, and their interactions with commonly expressed genetic and epigenetic alterations are undefined but nonetheless highly relevant to combinatorial treatments. METHOD...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: Garber, Sarah T., Hashimoto, Yuuri, Weathers, Shiao-Pei, Xiu, Joanne, Gatalica, Zoran, Verhaak, Roel G. W., Zhou, Shouhao, Fuller, Gregory N., Khasraw, Mustafa, de Groot, John, Reddy, Sandeep K., Spetzler, David, Heimberger, Amy B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Basic and Translational Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035527/
https://ncbi.nlm.nih.gov/pubmed/27370400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now132
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