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Population bias in somatic measurement of microsatellite instability status

Microsatellite instability (MSI) is a key secondary effect of a defective DNA mismatch repair mechanism resulting in incorrectly replicated microsatellites in many malignant tumors. Historically, MSI detection has been performed by fragment analysis (FA) on a panel of representative genomic markers....

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Saul, Michelle, Poorman, Kelsey, Tae, Hongseok, Vanderwalde, Ari, Stafford, Phillip, Spetzler, David, Korn, Wolfgang M., Gatalica, Zoran, Swensen, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476819/
https://ncbi.nlm.nih.gov/pubmed/32644297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3294
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