Exome-Wide Somatic Microsatellite Variation Is Altered in Cells with DNA Repair Deficiencies

Microsatellites (MST), tandem repeats of 1–6 nucleotide motifs, are mutational hot-spots with a bias for insertions and deletions (INDELs) rather than single nucleotide polymorphisms (SNPs). The majority of MST instability studies are limited to a small number of loci, the Bethesda markers, which ar...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Vaksman, Zalman, Fonville, Natalie C., Tae, Hongseok, Garner, Harold R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234249/
https://ncbi.nlm.nih.gov/pubmed/25402475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110263
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