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Estrogen receptor variant ER‐α36 promotes tamoxifen agonist activity in glioblastoma cells

Glioblastoma (GBM) is a highly infiltrative and malignant primary brain tumor. Despite aggressive therapy, patients with GBM have a dismal prognosis with median survival of approximately 1 year. Tamoxifen (TAM), a selective estrogen receptor modulator (SERM), has been used to treat GBM for many year...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Qu, Chao, Ma, Jingyun, Zhang, Yejun, Han, Chao, Huang, Liang, Shen, Liming, Li, Hongyan, Wang, Xiaobo, Liu, Jing, Zou, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317923/
https://ncbi.nlm.nih.gov/pubmed/30417588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13868
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