An in vivo immunotherapy screen of costimulatory molecules identifies Fc-OX40L as a potent reagent for the treatment of established murine gliomas

PURPOSE: We tested the combination of a tumor lysate vaccine with a panel of costimulatory molecules to identify an immunotherapeutic approach capable of curing established murine gliomas. EXPERIMENTAL DESIGN: Glioma-bearing mice were primed with a tumor lysate vaccine, followed by systemic administ...

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Detalhes bibliográficos
Main Authors: Murphy, Katherine A., Lechner, Melissa G., Popescu, Flavia E., Bedi, Jessica, Decker, Stacy A., Hu, Peisheng, Erickson, Jami R., O’Sullivan, M. Gerard, Swier, Lauryn, Salazar, Andres M., Olin, Michael R., Epstein, Alan L., Ohlfest, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432688/
https://ncbi.nlm.nih.gov/pubmed/22781551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0990
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