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Therapeutic strategies for the costimulatory molecule OX40 in T-cell-mediated immunity

The T cell co-stimulatory molecule OX40 and its cognate ligand OX40L have attracted broad research interest as a therapeutic target in T cell-mediated diseases. Accumulating preclinical evidence highlights the therapeutic efficacy of both agonist and blockade of the OX40–OX40L interaction. Despite t...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Fu, Yu, Lin, Qing, Zhang, Zhirong, Zhang, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049610/
https://ncbi.nlm.nih.gov/pubmed/32140389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.08.010
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