STEM-03. WAVE1 KNOCKDOWN ENHANCES THE ANTITUMOR EFFICACY IN PRIMARY GLIOBLASTOMA NEUROSPHERES

INTRODUCTION: Despite multi-model therapies that include maximal surgical resection, radiation, chemotherapy, and tumor treating fields, the median survival of Glioblastoma (GBM) patients is around 15 months. WASP-family verprolin homologous protein 1 (WAVE1) is a downstream effector that receives s...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Namagiri, Sriya, Thammegowda, Shilpa, Sur, Hannah, Vézina, Amélie, Chowdhury, Ashis, Maric, Dragan, Gangaplara, Arunakumar, Edwards, Nancy, Jackson, Sadhana, Ray-Chaudhury, Abhik, Heiss, John, Banasavadi-Siddegowda, Yeshavanth Kumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Cancer Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651572/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.820
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