STEM-16. DUAL INHIBITION OF PROTEIN ARGININE METHYLTRANSFERASE 5 AND PROTEIN PHOSPHATASE 2A ENHANCES THE ANTI-TUMOR EFFICACY IN PRIMARY GLIOBLASTOMA NEUROSPHERES

INTRODUCTION: Glioblastoma (GBM) is the most common malignant primary brain tumor and has a heterogeneous tumor cell population. The median survival of GBM patients is less than two years with current multi-model therapy of maximal surgical resection followed by chemotherapy, radiation and tumor tre...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Sur, Hannah, Gangaplara, Arunakumar, Wang, Xiang, Ray-Chaudhury, Abhik, Zhuang, Zhengping, Kumar, Sachin, Heiss, John, Young Yoo, Ji, Kaur, Balveen, Kumar Banasavadi-Siddegowda, Yeshavanth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847244/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.989
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