All-atomic Molecular Dynamic Studies of Human CDK8: Insight into the A-loop, Point Mutations and Binding with Its Partner CycC

Por Xu, Wu, Amire-Brahimi, Benjamin, Xie, Xiao-Jun, Huang, Liying, Ji, Jun-Yuan
Publicado em 2014

Orally Bioavailable Potent Soluble Epoxide Hydrolase Inhibitors

Por Hwang, Sung Hee, Tsai, Hsing-Ju, Liu, Jun-Yan, Morisseau, Christophe, Hammock, Bruce D.
Publicado em 2007

Biologically Active Ester Derivatives as Potent Inhibitors of the Soluble Epoxide Hydrolase

Por Kim, In-Hae, Nishi, Kosuke, Kasagami, Takeo, Morisseau, Christophe, Liu, Jun-Yan, Tsai, Hsing-Ju, Hammock, Bruce D.
Publicado em 2012

Design and synthesis of a novel photoaffinity probe for labelling EGF receptor tyrosine kinases

Por Zheng, You-Guang, Wu, Xiao-Qing, Su, Jun, Jiang, Ping, Xu, Liang, Gao, Jian, Cai, Bin, Ji, Min
Publicado no J Enzyme Inhib Med Chem (2017)

Design, synthesis, and evaluation of curcumin analogues as potential inhibitors of bacterial sialidase

Por Kim, Bo Ram, Park, Ji-Young, Jeong, Hyung Jae, Kwon, Hyung-Jun, Park, Su-Jin, Lee, In-Chul, Ryu, Young Bae, Lee, Woo Song
Publicado no J Enzyme Inhib Med Chem (2018)

Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors

Por Cuny, Gregory D., Ulyanova, Natalia P., Patnaik, Debasis, Liu, Ji-Feng, Lin, Xiangjie, Auerbach, Ken, Ray, Soumya S., Xian, Jun, Glicksman, Marcie A., Stein, Ross L., Higgins, Jonathan M.G.
Publicado em 2012

Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors

Por Cuny, Gregory D., Robin, Maxime, Ulyanova, Natalia P., Patnaik, Debasis, Pique, Valerie, Casano, Gilles, Liu, Ji-Feng, Lin, Xiangjie, Xian, Jun, Glicksman, Marcie A., Stein, Ross L., Higgins, Jonathan M.G.
Publicado em 2010

Bis-Aryl Urea Derivatives as Potent and Selective LIM Kinase (Limk) Inhibitors

Por Yin, Yan, Zheng, Ke, Eid, Nibal, Howard, Shannon, Jeong, Ji-Hak, Yi, Fei, Guo, Jia, Park, Chul M, Bibian, Mathieu, Wu, Weilin, Hernandez, Pamela, Park, HaJeung, Wu, Yuntao, Luo, Jun-Li, LoGrasso, Philip V., Feng, Yangbo
Publicado no J Med Chem (2015)

Pathogenic Bacterial Proteins and their Anti-Inflammatory Effects in the Eukaryotic Host

Por Sun, Jun
Publicado em 2009

Distinct biological effects of golgicide a derivatives on larval and adult mosquitoes

Por Mack, Daniel J., Isoe, Jun, Miesfeld, Roger L., Njardarson, Jon T.
Publicado em 2012

Discovery of a Highly Potent, Orally Active Mitosis/Angiogenesis Inhibitor R1530 for the Treatment of Solid Tumors

Por Liu, Jin-Jun, Higgins, Brian, Ju, Grace, Kolinsky, Kenneth, Luk, Kin-Chun, Packman, Kathryn, Pizzolato, Giacomo, Ren, Yi, Thakkar, Kshitij, Tovar, Christian, Zhang, Zhuming, Wovkulich, Peter M.
Publicado em 2013

α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer’s Disease

Por Toyohara, Jun, Hashimoto, Kenji
Publicado em 2010

Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases

Por Bhat, Shridhar, Olaleye, Omonike, Meyer, Kirsten J., Shi, Wanliang, Zhang, Ying, Liu, Jun O.
Publicado em 2012

The Med1 Subunit of the Mediator Complex Induces Liver Cell Proliferation and Is Phosphorylated by AMP Kinase

Por Viswakarma, Navin, Jia, Yuzhi, Bai, Liang, Gao, Qian, Lin, Bingliang, Zhang, Xiaohong, Misra, Parimal, Rana, Ajay, Jain, Sanjay, Gonzalez, Frank J., Zhu, Yi-Jun, Thimmapaya, Bayar, Reddy, Janardan K.
Publicado em 2013

Analysis of nine compounds from Alpinia oxyphylla fruit at different harvest time using UFLC-MS/MS and an extraction method optimized by orthogonal design

Por Li, Yong-Hui, Chen, Feng, Wang, Jun-fang, Wang, Yong, Zhang, Jun-Qing, Guo, Tao
Publicado em 2013

Identification and validation of protein targets of bioactive small molecules

Por Titov, Denis V., Liu, Jun O.
Publicado em 2011

Macrocarpal C isolated from Eucalyptus globulus inhibits dipeptidyl peptidase 4 in an aggregated form

Por Kato, Eisuke, Kawakami, Kazuhiro, Kawabata, Jun
Publicado no J Enzyme Inhib Med Chem (2017)

Structure–activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors

Por Cuny, Gregory D., Robin, Maxime, Ulyanova, Natalia P., Patnaik, Debasis, Pique, Valerie, Casano, Gilles, Liu, Ji-Feng, Lin, Xiangjie, Xian, Jun, Glicksman, Marcie A., Stein, Ross L., Higgins, Jonathan M. G.
Publicado em 2010

4′-Methyl-4,5′-bithiazole-based correctors of defective ΔF508-CFTR cellular processing

Por Yoo, Choong Leol, Yu, Gui Jun, Yang, Baoxue, Robins, Lori I., Verkman, A.S., Kurth, Mark J.
Publicado em 2008

Synthesis and characterisation of (Z)-styrylbenzene derivatives as potential selective anticancer agents

Por Xin, Ya-Bing, Li, Jia-Jun, Zhang, Hong-Jian, Ma, Jun, Liu, Xin, Gong, Guo-Hua, Tian, Yu-Shun
Publicado no J Enzyme Inhib Med Chem (2018)