Serum- and Glucocorticoid-Inducible Kinase 1 Confers Protection in Cell-Based and in In Vivo Neurotoxin Models via the c-Jun N-Terminal Kinase Signaling Pathway

Por Iqbal, Sarah, Howard, Shannon, LoGrasso, Philip V.
Publicado no Mol Cell Biol (2015)

Pharmacological Inhibition of c-Jun N-terminal Kinase Reduces Food Intake and Sensitizes Leptin’s Anorectic Signaling Actions

Por Gao, Su, Howard, Shannon, LoGrasso, Philip V.
Publicado no Sci Rep (2017)

Blocking c-Jun N-terminal Kinase (JNK) Translocation to the Mitochondria Prevents 6-Hydroxydopamine-induced Toxicity in Vitro and in Vivo

Por Chambers, Jeremy W., Howard, Shannon, LoGrasso, Philip V.
Publicado em 2013

Inhibition of JNK Mitochondrial Localization and Signaling Is Protective against Ischemia/Reperfusion Injury in Rats

Por Chambers, Jeremy W., Pachori, Alok, Howard, Shannon, Iqbal, Sarah, LoGrasso, Philip V.
Publicado em 2013

Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease

Por Grassi, Diego, Howard, Shannon, Zhou, Minghai, Diaz-Perez, Natalia, Urban, Nicolai T., Guerrero-Given, Debbie, Kamasawa, Naomi, Volpicelli-Daley, Laura A., LoGrasso, Philip, Lasmézas, Corinne Ida
Publicado no Proc Natl Acad Sci U S A (2018)

Microbial symbionts regulate the primary Ig repertoire

Por Chen, Yuezhou, Chaudhary, Neha, Yang, Nicole, Granato, Alessandra, Turner, Jacob A., Howard, Shannon L., Devereaux, Colby, Zuo, Teng, Shrestha, Akritee, Goel, Rishi R., Neuberg, Donna, Wesemann, Duane R.
Publicado no J Exp Med (2018)

Small Molecule c-jun-N-Terminal Kinase Inhibitors Protect Dopaminergic Neurons in a Model of Parkinson’s Disease

Por Chambers, Jeremy W., Pachori, Alok, Howard, Shannon, Ganno, Michelle, Hansen, Donald, Kamenecka, Ted, Song, Xinyi, Duckett, Derek, Chen, Weimin, Ling, Yuan Yuan, Cherry, Lisa, Cameron, Michael D., Lin, Li, Ruiz, Claudia H., LoGrasso, Philip
Publicado em 2011

Bis-Aryl Urea Derivatives as Potent and Selective LIM Kinase (Limk) Inhibitors

Por Yin, Yan, Zheng, Ke, Eid, Nibal, Howard, Shannon, Jeong, Ji-Hak, Yi, Fei, Guo, Jia, Park, Chul M, Bibian, Mathieu, Wu, Weilin, Hernandez, Pamela, Park, HaJeung, Wu, Yuntao, Luo, Jun-Li, LoGrasso, Philip V., Feng, Yangbo
Publicado no J Med Chem (2015)