Microbial symbionts regulate the primary Ig repertoire

The ability of immunoglobulin (Ig) to recognize pathogens is critical for optimal immune fitness. Early events that shape preimmune Ig repertoires, expressed on IgM(+) IgD(+) B cells as B cell receptors (BCRs), are poorly defined. Here, we studied germ-free mice and conventionalized littermates to e...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Exp Med
Asıl Yazarlar: Chen, Yuezhou, Chaudhary, Neha, Yang, Nicole, Granato, Alessandra, Turner, Jacob A., Howard, Shannon L., Devereaux, Colby, Zuo, Teng, Shrestha, Akritee, Goel, Rishi R., Neuberg, Donna, Wesemann, Duane R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2018
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940265/
https://ncbi.nlm.nih.gov/pubmed/29588346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171761
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