Microbial symbionts regulate the primary Ig repertoire

The ability of immunoglobulin (Ig) to recognize pathogens is critical for optimal immune fitness. Early events that shape preimmune Ig repertoires, expressed on IgM(+) IgD(+) B cells as B cell receptors (BCRs), are poorly defined. Here, we studied germ-free mice and conventionalized littermates to e...

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Podrobná bibliografie
Vydáno v:J Exp Med
Hlavní autoři: Chen, Yuezhou, Chaudhary, Neha, Yang, Nicole, Granato, Alessandra, Turner, Jacob A., Howard, Shannon L., Devereaux, Colby, Zuo, Teng, Shrestha, Akritee, Goel, Rishi R., Neuberg, Donna, Wesemann, Duane R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940265/
https://ncbi.nlm.nih.gov/pubmed/29588346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171761
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