Microbial symbionts regulate the primary Ig repertoire

The ability of immunoglobulin (Ig) to recognize pathogens is critical for optimal immune fitness. Early events that shape preimmune Ig repertoires, expressed on IgM(+) IgD(+) B cells as B cell receptors (BCRs), are poorly defined. Here, we studied germ-free mice and conventionalized littermates to e...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Chen, Yuezhou, Chaudhary, Neha, Yang, Nicole, Granato, Alessandra, Turner, Jacob A., Howard, Shannon L., Devereaux, Colby, Zuo, Teng, Shrestha, Akritee, Goel, Rishi R., Neuberg, Donna, Wesemann, Duane R.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940265/
https://ncbi.nlm.nih.gov/pubmed/29588346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171761
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