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Pharmacological Inhibition of c-Jun N-terminal Kinase Reduces Food Intake and Sensitizes Leptin’s Anorectic Signaling Actions

The role for c-Jun N-terminal Kinase (JNK) in the control of feeding and energy balance is not well understood. Here, by use of novel and highly selective JNK inhibitors, we investigated the actions of JNK in the control of feeding and body weight homeostasis. In lean mice, intraperitoneal (i.p.) or...

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Publicat a:Sci Rep
Autors principals: Gao, Su, Howard, Shannon, LoGrasso, Philip V.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292945/
https://ncbi.nlm.nih.gov/pubmed/28165482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41795
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