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Enzyme Kinetics and Interaction Studies for Human JNK1β1 and Substrates Activating Transcription Factor 2 (ATF2) and c-Jun N-terminal kinase (c-Jun)

c-Jun N-terminal kinase (JNK) is a stress signal transducer linked to cell death, and survival. JNK1 has been implicated in obesity, glucose intolerance, and insulin resistance. In this study we report the kinetic mechanism for JNK1β1 with transcription factors ATF2 and c-Jun along with interaction...

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Detalhes bibliográficos
Main Authors: Figuera-Losada, Mariana, LoGrasso, Philip V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339953/
https://ncbi.nlm.nih.gov/pubmed/22351776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.323766
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