Enzyme Kinetics and Interaction Studies for Human JNK1β1 and Substrates Activating Transcription Factor 2 (ATF2) and c-Jun N-terminal kinase (c-Jun)

Por Figuera-Losada, Mariana, LoGrasso, Philip V.
Publicado em 2012

Inhibition of Microglia Activation as a Phenotypic Assay in Early Drug Discovery

Por Figuera-Losada, Mariana, Rojas, Camilo, Slusher, Barbara S.
Publicado em 2013

Targeting the Glutamatergic System for the Treatment of HIV-Associated Neurocognitive Disorders

Por Potter, Michelle C., Figuera-Losada, Mariana, Rojas, Camilo, Slusher, Barbara S.
Publicado em 2013

Selective Inhibition of Mitochondrial JNK Signaling Achieved Using Peptide Mimicry of the Sab Kinase Interacting Motif-1 (KIM1)

Por Chambers, Jeremy W., Cherry, Lisa, Laughlin, John D., Figuera-Losada, Mariana, LoGrasso, Philip V.
Publicado em 2011

Development of a primary microglia screening assay and its use to characterize inhibition of system x(c)(-) by erastin and its analogs

Por Figuera-Losada, Mariana, Thomas, Ajit G., Stathis, Marigo, Stockwell, Brent R., Rojas, Camilo, Slusher, Barbara S.
Publicado no Biochem Biophys Rep (2017)

EFFECTS ON HUMAN PLASMINOGEN CONFORMATION AND ACTIVATION RATE CAUSED BY INTERACTION WITH VEK-30, A PEPTIDE DERIVED FROM THE GROUP A STREPTOCOCCAL M-LIKE PROTEIN (PAM)*

Por Figuera-Losada, Mariana, Ranson, Marie, Sanderson-Smith, Martina L., Walker, Mark J., Castellino, Francis J., Prorok, Mary
Publicado em 2010

Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases

Por Laughlin, John D., Nwachukwu, Jerome C., Figuera-Losada, Mariana, Cherry, Lisa, Nettles, Kendall W., LoGrasso, Philip V.
Publicado em 2012

A Small Molecule Bidentate-Binding Dual Inhibitor Probe of the LRRK2 and JNK Kinases

Por Feng, Yangbo, Chambers, Jeremy W., Iqbal, Sarah, Koenig, Marcel, Park, HaJeung, Cherry, Lisa, Hernandez, Pamela, Figuera-Losada, Mariana, LoGrasso, Philip V.
Publicado em 2013

Synthesis, Biological Evaluation, X-Ray Structure, and Pharmacokinetics of Aminopyrimidine c-jun-N-terminal Kinase (JNK) Inhibitors

Por Kamenecka, Ted, Jiang, Rong, Song, Xinyi, Duckett, Derek, Chen, Weimin, Ling, Yuan Yuan, Habel, Jeff, Laughlin, John D., Chambers, Jeremy, Figuera-Losada, Mariana, Cameron, Michael D., Lin, Li, Ruiz, Claudia H., LoGrasso, Philip V.
Publicado em 2010

Cambinol, a Novel Inhibitor of Neutral Sphingomyelinase 2 Shows Neuroprotective Properties

Por Figuera-Losada, Mariana, Stathis, Marigo, Dorskind, Joelle M., Thomas, Ajit G., Bandaru, Veera Venkata Ratnam, Yoo, Seung-Wan, Westwood, Nicholas J., Rogers, Graeme W., McArthur, Justin C., Haughey, Norman J., Slusher, Barbara S., Rojas, Camilo
Publicado no PLoS One (2015)