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EFFECTS ON HUMAN PLASMINOGEN CONFORMATION AND ACTIVATION RATE CAUSED BY INTERACTION WITH VEK-30, A PEPTIDE DERIVED FROM THE GROUP A STREPTOCOCCAL M-LIKE PROTEIN (PAM)*

In vertebrates, fibrinolysis is primarily carried out by the serine protease plasmin (Pm), which is derived from activation of the zymogen precursor, plasminogen (Pg). One of the most distinctive features of Pg/Pm is the presence of five homologous kringle (K) domains. These structural elements poss...

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Detalhes bibliográficos
Main Authors: Figuera-Losada, Mariana, Ranson, Marie, Sanderson-Smith, Martina L., Walker, Mark J., Castellino, Francis J., Prorok, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846993/
https://ncbi.nlm.nih.gov/pubmed/20152941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.01.019
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