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Inhibition of JNK Mitochondrial Localization and Signaling Is Protective against Ischemia/Reperfusion Injury in Rats

To build upon recent findings that mitochondrial JNK signaling is inhibited by selectively blocking the interaction between JNK and Sab, we utilized a cell-permeable peptide to demonstrate that ischemia/reperfusion (I/R) injury could be protected in vivo and that JNK mitochondrial signaling was the...

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Detalhes bibliográficos
Main Authors: Chambers, Jeremy W., Pachori, Alok, Howard, Shannon, Iqbal, Sarah, LoGrasso, Philip V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567652/
https://ncbi.nlm.nih.gov/pubmed/23258542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.406777
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