Design, synthesis, and evaluation of curcumin analogues as potential inhibitors of bacterial sialidase

Sialidases are key virulence factors that remove sialic acid from the host cell surface glycan, unmasking receptors that facilitate bacterial adherence and colonisation. In this study, we developed potential agents for treating bacterial infections caused by Streptococcus pneumoniae Nan A that inhib...

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Detalles Bibliográficos
Publicado en:J Enzyme Inhib Med Chem
Autores principales: Kim, Bo Ram, Park, Ji-Young, Jeong, Hyung Jae, Kwon, Hyung-Jun, Park, Su-Jin, Lee, In-Chul, Ryu, Young Bae, Lee, Woo Song
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104608/
https://ncbi.nlm.nih.gov/pubmed/30126306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1488695
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