Design, synthesis, and evaluation of curcumin analogues as potential inhibitors of bacterial sialidase

Sialidases are key virulence factors that remove sialic acid from the host cell surface glycan, unmasking receptors that facilitate bacterial adherence and colonisation. In this study, we developed potential agents for treating bacterial infections caused by Streptococcus pneumoniae Nan A that inhib...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Kim, Bo Ram, Park, Ji-Young, Jeong, Hyung Jae, Kwon, Hyung-Jun, Park, Su-Jin, Lee, In-Chul, Ryu, Young Bae, Lee, Woo Song
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104608/
https://ncbi.nlm.nih.gov/pubmed/30126306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1488695
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