Design, synthesis, and evaluation of curcumin analogues as potential inhibitors of bacterial sialidase

Sialidases are key virulence factors that remove sialic acid from the host cell surface glycan, unmasking receptors that facilitate bacterial adherence and colonisation. In this study, we developed potential agents for treating bacterial infections caused by Streptococcus pneumoniae Nan A that inhib...

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Bibliographische Detailangaben
Veröffentlicht in:J Enzyme Inhib Med Chem
Hauptverfasser: Kim, Bo Ram, Park, Ji-Young, Jeong, Hyung Jae, Kwon, Hyung-Jun, Park, Su-Jin, Lee, In-Chul, Ryu, Young Bae, Lee, Woo Song
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104608/
https://ncbi.nlm.nih.gov/pubmed/30126306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1488695
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