A carregar...
4′-Methyl-4,5′-bithiazole-based correctors of defective ΔF508-CFTR cellular processing
The synthesis and ΔF508-CFTR corrector activity of a 148-member methylbithiazole-based library is reported. Synthetic routes were devised and optimized to generate methylbithiazole analogs in four steps. Corrector potency and efficacy was assayed using epithelial cells expressing human ΔF508-CFTR. T...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166558/ https://ncbi.nlm.nih.gov/pubmed/18394886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.03.037 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|