Constrained Bithiazoles: Small Molecule Correctors of Defective ΔF508–CFTR Protein Trafficking

[Image: see text] Conformationally constrained bithiazoles were previously found to have improved efficacy over nonconstrained bithiazoles for correction of defective cellular processing of the ΔF508 mutant cystic fibrosis transmembrane conductance regulator (CFTR) protein. In this study, two sets o...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Coffman, Keith C., Nguyen, Huy H., Phuan, Puay-Wah, Hudson, Brandi M., Yu, Gui J., Bagdasarian, Alex L., Montgomery, Deanna, Lodewyk, Michael W., Yang, Baoxue, Yoo, Choong L., Verkman, A. S., Tantillo, Dean J., Kurth, Mark J.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2014
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136667/
https://ncbi.nlm.nih.gov/pubmed/25061695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5007885
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires