Constrained Bithiazoles: Small Molecule Correctors of Defective ΔF508–CFTR Protein Trafficking

[Image: see text] Conformationally constrained bithiazoles were previously found to have improved efficacy over nonconstrained bithiazoles for correction of defective cellular processing of the ΔF508 mutant cystic fibrosis transmembrane conductance regulator (CFTR) protein. In this study, two sets o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Coffman, Keith C., Nguyen, Huy H., Phuan, Puay-Wah, Hudson, Brandi M., Yu, Gui J., Bagdasarian, Alex L., Montgomery, Deanna, Lodewyk, Michael W., Yang, Baoxue, Yoo, Choong L., Verkman, A. S., Tantillo, Dean J., Kurth, Mark J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2014
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136667/
https://ncbi.nlm.nih.gov/pubmed/25061695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5007885
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