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1
Por Krishnamoorthy, Lakshmi, Cotruvo, Joseph A., Chan, Jefferson, Kaluarachchi, Harini, Muchenditsi, Abigael, Pendyala, Venkata S., Jia, Shang, Aron, Allegra T., Ackerman, Cheri M., Vander Wal, Mark N., Guan, Timothy, Smaga, Lukas P., Farhi, Samouil L., New, Elizabeth J., Lutsenko, Svetlana, Chang, Christopher J.
Publicado no Nat Chem Biol (2016)
“... with pharmacological alterations in copper status and imaging studies in a 3T3-L1 white adipocyte model, we demonstrate...”Publicado no Nat Chem Biol (2016)
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2
“...Although a plurality of drugs target G-protein-coupled receptors (GPCRs), most have emerged from...”
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3
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Por Johnson, Andy L., Aravind, L., Shulzhenko, Natalia, Morgun, Andriy, Choi, See-Young, Crockford, Tanya L., Lambe, Teresa, Domaschenz, Heather, Kucharska, Edyta, Zheng, Lixin, Vinuesa, Carola C., Lenardo, Michael J., Goodnow, Christopher C., Cornall, Richard J., Schwartz, Ronald H.
Publicado em 2009
“... this issue, we used ethylnitrosourea mutagenesis to identify a novel T-lineage-specific gene, Themis, which...”Publicado em 2009
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5
Por Blanchard, Guy B., Kabla, Alexandre J., Schultz, Nora L., Butler, Lucy C., Sanson, Benedicte, Gorfinkiel, Nicole, Mahadevan, L., Adams, Richard J.
Publicado no Nat Methods (2009)
“...The dynamic reshaping of tissues during morphogenesis results from a combination of individual cell...”Publicado no Nat Methods (2009)
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6
Por Trapnell, Cole, Williams, Brian A., Pertea, Geo, Mortazavi, Ali, Kwan, Gordon, van Baren, Marijke J., Salzberg, Steven L., Wold, Barbara J., Pachter, Lior
Publicado em 2010
“... and abundance estimation(1-3). We introduce an algorithm for transcript assembly coupled with a statistical...”Publicado em 2010
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7
Por Reichow, Steve L., Clemens, Daniel M., Freites, J. Alfredo, Németh-Cahalan, Karin L., Heyden, Matthias, Tobias, Douglas J., Hall, James E., Gonen, Tamir
Publicado em 2013
“...Calmodulin (CaM) is a universal regulatory protein that communicates the presence of calcium to its...”Publicado em 2013
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8
Por Hong, Guosong, Diao, Shuo, Chang, Junlei, Antaris, Alexander L., Chen, Changxin, Zhang, Bo, Zhao, Su, Atochin, Dmitriy N., Huang, Paul L., Andreasson, Katrin I., Kuo, Calvin J., Dai, Hongjie
Publicado no Nat Photonics (2014)
“... fluorescence imaging reaching a depth of >2 mm in mouse brain with sub-10 micrometre resolution. An imaging...”Publicado no Nat Photonics (2014)
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9
Por O’Brien, Valerie P., Hannan, Thomas J., Yu, Lu, Livny, Jonathan, Roberson, Elisha D. O., Schwartz, Drew J., Souza, Spenser, Mendelsohn, Cathy L., Colonna, Marco, Lewis, Amanda L., Hultgren, Scott J.
Publicado no Nat Microbiol (2016)
“... is often a significant risk factor for developing new infections. For urinary tract infection (UTI), a...”Publicado no Nat Microbiol (2016)
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10
Por Khawaja, Anthony P, Cooke Bailey, Jessica N, Wareham, Nicholas J., Scott, Robert A., Simcoe, Mark, Igo, Robert P., Song, Yeunjoo E., Wojciechowski, Robert, Cheng, Ching-Yu, Khaw, Peng T, Pasquale, Louis R, Haines, Jonathan L., Foster, Paul J, Wiggs, Janey L, Hammond, Chris J, Hysi, Pirro G
Publicado no Nat Genet (2018)
“... for primary open-angle glaucoma (POAG).3,4 Here we present a meta-analysis of 139,555 European participants...”Publicado no Nat Genet (2018)
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11
Por Burkhart, Brandon J., Hudson, Graham A., Dunbar, Kyle L., Mitchell, Douglas A.
Publicado no Nat Chem Biol (2015)
“...Ribosomally synthesized and posttranslationally modified peptides (RiPPs) are a rapidly growing...”Publicado no Nat Chem Biol (2015)
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12
Por Taslimi, Amir, Vrana, Justin D., Chen, Daniel, Borinskaya, Sofya, Mayer, Bruce J., Kennedy, Matthew J., Tucker, Chandra L.
Publicado em 2014
“..., allowing spatiotemporal control of cellular processes with light. Here we report the development of a new...”Publicado em 2014
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13
Por Srinivasan, Prakash, Yasgar, Adam, Luci, Diane K., Beatty, Wandy L., Hu, Xin, Andersen, John, Narum, David L., Moch, J. Kathleen, Sun, Hongmao, Haynes, J. David, Maloney, David J., Jadhav, Ajit, Simeonov, Anton, Miller, Louis H.
Publicado em 2013
“..., drives the search for new classes of chemotherapeutic agents. Current discovery is primarily directed...”Publicado em 2013
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14
Por H. Dean Hosgood, Madelyn Klugman, Keitaro Matsuo, Alexandra J. White, Atsuko Sadakane, Xiao-Ou Shu, Ruy Lopez-Ridaura, Aesun Shin, Ichiro Tsuji, Reza Malekzadeh, Nolwenn Noisel, Parveen Bhatti, Gong Yang, Eiko Saito, Shafiur Rahman, Wei Hu, Bryan Bassig, George Downward, Roel Vermeulen, Xiaonan Xue, Thomas Rohan, Sarah K. Abe, Philippe Broët, Eric J. Grant, Trevor J. B. Dummer, Nat Rothman, Manami Inoue, Martin Lajous, Keun-Young Yoo, Hidemi Ito, Dale P. Sandler, Habib Ashan, Wei Zheng, Paolo Boffetta, Qing Lan
Publicado em 2019-07-01
“... (including >15 million in the US) exposed. HAP from coal use is a human lung carcinogen, yet...”Publicado em 2019-07-01
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15
Por Li, Songlin, Overman, Justine J, Katsman, Diana, Kozlov, Serguei V, Donnelly, Christopher J, Twiss, Jeffery L, Giger, Roman J, Coppola, Giovanni, Geschwind, Daniel H, Carmichael, S Thomas
Publicado em 2010
“... new connection after stroke is not known. We selectively isolated neurons that sprout a new connection...”Publicado em 2010
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16
Por Krishnamurty, Ratika, Brigham, Jennifer L., Leonard, Stephen E., Ranjitkar, Pratistha, Larson, Eric T., Dale, Edward J., Merritt, Ethan A., Maly, Dustin J.
Publicado em 2012
“... and for performing inhibitor selectivity screens. Here we describe a new crosslinking strategy that enables rapid...”Publicado em 2012
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17
Por Amiram, Miriam, Haimovich, Adrian D, Fan, Chenguang, Wang, Yane-Shih, Aerni, Hans-Rudolf, Ntai, Ioanna, Moonan, Daniel W, Ma, Natalie J, Rovner, Alexis J, Hong, Seok Hoon, Kelleher, Neil L, Goodman, Andrew L, Jewett, Michael C, Söll, Dieter, Rinehart, Jesse, Isaacs, Farren J
Publicado no Nat Biotechnol (2015)
“... of proteins with diverse new chemistries. However, this technology has been largely restricted to proteins...”Publicado no Nat Biotechnol (2015)
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18
Por Bugaj, L. J., Spelke, D. P., Mesuda, C.K., Varedi, M., Kane, R.S., Schaffer, D.V.
Publicado no Nat Commun (2015)
“... using non-covalent interactions with engineered Arabidopsis Cryptochrome 2 (Cry2). CLICR offers a...”Publicado no Nat Commun (2015)
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19
Por Martínez, I. A., Roldán, É., Dinis, L., Petrov, D., Parrondo, J. M. R., Rica, R. A.
Publicado no Nat Phys (2016)
“...-time efficiency, showing that the Carnot bound can be surpassed for a small number of non-equilibrium...”Publicado no Nat Phys (2016)
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20
Por Kurita, Mitsumasa, Holloway, Terrell, García-Bea, Aintzane, Kozlenkov, Alexey, Friedman, Allyson K., Moreno, José L., Heshmati, Mitra, Golden, Sam A., Kennedy, Pamela J., Takahashi, Nagahide, Dietz, David M., Mocci, Giuseppe, Gabilondo, Ane M., Hanks, James, Umali, Adrienne, Callado, Luis F., Gallitano, Amelia L., Neve, Rachael L., Shen, Li, Buxbaum, Joseph D., Han, Ming-Hu, Nestler, Eric J., Meana, J. Javier, Russo, Scott J., González-Maeso, Javier
Publicado em 2012
“... their therapeutic-like effects. These observations support the view of HDAC2 as a promising new target to improve...”Publicado em 2012
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