Resultados da pesquisa - (( j amp camp can new ) OR ((( j nail clase con noe ) OR ( el vino amp can non ))))

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Endosomal generation of cAMP in GPCR signaling

Por Vilardaga, Jean-Pierre, Jean-Alphonse, Frederic G., Gardella, Thomas J.
Publicado no Nat Chem Biol (2014)

“...It has been widely assumed that the production of the ubiquitous second messenger cyclic AMP, which...”
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The Escherichia coli cAMP receptor protein bound at a single target can activate transcription...

Por El-Robh, Mohamed Samir, Busby, Stephen J W
Publicado em 2002

“... coli cAMP receptor protein (CRP), a factor known to activate transcription initiation at target...”
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The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response

Por Roberts, Maxine J., Broome, Rebecca E., Kent, Toby C., Charlton, Steven J., Rosethorne, Elizabeth M.
Publicado no Respir Res (2018)

“...), and explore which can increase cAMP levels, and are most efficacious at inhibiting proliferation...”
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Protein synthesis during acquisition of long-term facilitation is needed for the persistent loss of regulatory subunits of the Aplysia cAMP-dependent protein kinase.

Por Bergold, P J, Sweatt, J D, Winicov, I, Weiss, K R, Kandel, E R, Schwartz, J H
Publicado em 1990

“... short-term or long-term presynaptic facilitation of Aplysia sensory-to-motor synapses. The cAMP...”
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A Gα(s) DREADD Mouse for Selective Modulation of cAMP Production in Striatopallidal Neurons

Por Farrell, Martilias S, Pei, Ying, Wan, Yehong, Yadav, Prem N, Daigle, Tanya L, Urban, Daniel J, Lee, Hyeong-Min, Sciaky, Noah, Simmons, Arkeen, Nonneman, Randal J, Huang, Xi-Ping, Hufeisen, Sandy J, Guettier, Jean-Marc, Moy, Sheryl S, Wess, Jürgen, Caron, Marc G, Calakos, Nicole, Roth, Bryan L
Publicado em 2013

“...). We first show that in vitro, rM3Ds can couple to Gα(olf) and induce cAMP accumulation in cultured...”
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The role of ventral striatal cAMP signaling in stress-induced behaviors

Por Plattner, Florian, Hayashi, Kanehiro, Hernandez, Adan, Benavides, David R., Tassin, Tara C., Tan, Chunfeng, Day, Jonathan, Fina, Maggy W., Yuen, Eunice Y., Yan, Zhen, Goldberg, Matthew S., Nairn, Angus C., Greengard, Paul, Nestler, Eric J., Taussig, Ronald, Nishi, Akinori, Houslay, Miles D., Bibb, James A.
Publicado no Nat Neurosci (2015)

“...The cAMP/PKA signaling cascade is a ubiquitous pathway acting downstream of multiple...”
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New DAG and cAMP Sensors Optimized for Live-Cell Assays in Automated Laboratories

Por Tewson, Paul H., Martinka, Scott, Shaner, Nathan C., Hughes, Thomas E., Quinn, Anne Marie
Publicado no J Biomol Screen (2015)

“... glycerol and another for cAMP, that are robust (Z′ > 0.7) and easily deployed on standard fluorescence...”
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cAMP Regulation of Airway Smooth Muscle Function

Por Billington, Charlotte K., Ojo, Oluwaseun O., Penn, Raymond B., Ito, Satoru
Publicado em 2012

“... the generation of intracellular cAMP, which in turn can activate the effector molecules cAMP-dependent protein...”
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Gene Expression and Transcription Factor Profiling Reveal Inhibition of Transcription Factor cAMP...

Por Brown, Helen J., Peng, Li, Harada, Josephine N., Walker, John R., Cole, Steven, Lin, Su-Fang, Zack, Jerome A., Chanda, Sumit K., Sun, Ren
Publicado em 2010

“... was the high level of cAMP-response element-binding protein (CREB)-response elements in RTA target genes. We...”
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The cAMP-responsive Rap1 Guanine Nucleotide Exchange Factor, Epac, Induces Smooth Muscle Relaxation by Down-regulation of RhoA Activity

Por Zieba, Bartosz J., Artamonov, Mykhaylo V., Jin, Li, Momotani, Ko, Ho, Ruoya, Franke, Aaron S., Neppl, Ronald L., Stevenson, Andra S., Khromov, Alexander S., Chrzanowska-Wodnicka, Magdalena, Somlyo, Avril V.
Publicado em 2011

“...)) phosphorylation and force. Cyclic nucleotides can reverse this process. We report a new mechanism of cAMP-mediated...”
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Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation

Por Wang, Zhiping, Dillon, Tara J., Pokala, Viji, Mishra, Snigdha, Labudda, Kirstin, Hunter, Brian, Stork, Philip J. S.
Publicado em 2006

“... of Rap1 by cyclic AMP (cAMP) can occur via cAMP-dependent protein kinase A (PKA)-independent and PKA...”
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Channeling of cAMP in PDE-PKA Complexes Promotes Signal Adaptation

Por Tulsian, Nikhil Kumar, Krishnamurthy, Srinath, Anand, Ganesh Srinivasan
Publicado no Biophys J (2017)

“... of cAMP rather than steady-state levels. The PDE8-RIα complex represents a new class of PDE-based...”
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Uncoupling Catalytic and Binding Functions in the cAMP-Dependent Protein Kinase A

Por Kim, Jonggul, Li, Geoffrey, Walters, Michael A., Taylor, Susan S., Veglia, Gianluigi
Publicado no Structure (2016)

“... signaling cascade; while their non-canonical role is to bind other kinases or substrates, acting...”
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Luminescence-activated nucleotide cyclase regulates spatial and temporal cAMP synthesis

Por Naim, Nyla, White, Alex D., Reece, Jeff M., Wankhede, Mamta, Zhang, Xuefeng, Vilardaga, Jean-Pierre, Altschuler, Daniel L.
Publicado no J Biol Chem (2019)

“...-biased cAMP signaling. Here, we introduce a new fusion protein consisting of a light-activated adenylyl...”
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Exchange Proteins Directly Activated by cAMP and Their Roles in Respiratory Syncytial Virus Infection

Por Choi, Eun-Jin, Ren, Yuping, Chen, Yu, Liu, Shengxuan, Wu, Wenzhe, Ren, Junping, Wang, Pingyuan, Garofalo, Roberto P., Zhou, Jia, Bao, Xiaoyong
Publicado no J Virol (2018)

“.... In this study, we discovered that an exchange protein directly activated by cyclic AMP (EPAC) can serve as a...”
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Short and Long-term memory in Drosophila require cAMP signaling in distinct neuron types

Por Blum, Allison L., Li, Wanhe, Cressy, Mike, Dubnau, Josh
Publicado em 2009

“... role for cAMP signaling in the mushroom body (MB). The Ca(++) responsive adenylyl cyclase rutabaga...”
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cAMP signal transduction in the heart: understanding spatial control for the development of novel therapeutic strategies

Por Zaccolo, Manuela
Publicado em 2009

“... the myocyte can decode the cAMP signal and generate the appropriate functional output to each individual...”
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State-Dependent cAMP Binding to Functioning HCN Channels Studied by Patch-Clamp Fluorometry

Por Wu, Shengjun, Vysotskaya, Zhanna V., Xu, Xinping, Xie, Changan, Liu, Qinglian, Zhou, Lei
Publicado em 2011

“... binding from channel gating. Here we studied the cyclic adenosine monophosphate (cAMP)-dependent gating...”
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Active Site Coupling in PDE:PKA Complexes Promotes Resetting of Mammalian cAMP Signaling

Por Krishnamurthy, Srinath, Moorthy, Balakrishnan Shenbaga, Xin Xiang, Lim, Xin Shan, Lim, Bharatham, Kavitha, Tulsian, Nikhil Kumar, Mihalek, Ivana, Anand, Ganesh S.
Publicado em 2014

“... that phosphodiesterases (PDEs) can catalyze dissociation of bound cAMP and thereby play an active role in cAMP signal...”
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Anti-diabetic biguanides inhibit hormone-induced intracellular Ca2+ concentration oscillations in rat hepatocytes.

Por Ubl, J J, Chen, S, Stucki, J W
Publicado em 1994

“... of the frequency. By contrast, agents which increase the cellular cyclic AMP (cAMP) concentration (glucagon...”
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