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Active Site Coupling in PDE:PKA Complexes Promotes Resetting of Mammalian cAMP Signaling
Cyclic 3′5′ adenosine monophosphate (cAMP)-dependent-protein kinase (PKA) signaling is a fundamental regulatory pathway for mediating cellular responses to hormonal stimuli. The pathway is activated by high-affinity association of cAMP with the regulatory subunit of PKA and signal termination is ach...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167538/ https://ncbi.nlm.nih.gov/pubmed/25229150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.050 |
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