Relationship between Dose, Drug Levels, and D2 Receptor Occupancy for the Atypical Antipsychotics Risperidone and Paliperidone

Por Muly, E. C., Votaw, J. R., Ritchie, J., Howell, L. L.
Publicado em 2012

Strategies to conserve salbutamol pressurized metered-dose inhaler stock levels amid COVID-19 drug shortage

Por Elbeddini, Ali, Tayefehchamani, Yasamin, Yang, Lucy
Publicado no Drugs Ther Perspect (2020)

Proof of Concept: Drug Selection? Or Dose Selection? Thoughts on Multiplicity Issues

Por Li, Qian H., Deng, Qiqi, Ting, Naitee
Publicado no Ther Innov Regul Sci (2021)

Clozapine-Related EEG Changes and Seizures: Dose and Plasma-Level Relationships

Por Varma, Seema, Bishara, Delia, Besag, Frank M. C., Taylor, David
Publicado em 2011

Drug-drug interaction between isavuconazole and tacrolimus: a case report indicating the need for tacrolimus drug-level monitoring

Por Kim, Tiffany, Jancel, Timothy, Kumar, Parag, Freeman, Alexandra F.
Publicado no J Clin Pharm Ther (2015)

Use of glomerular filtration rate estimating equations for drug dosing in HIV-positive patients

Por Okparavero, Aghogho A, Tighiouart, Hocine, Krishnasami, Zipporah, Wyatt, Christina M, Graham, Hiba, Hellinger, James, Inker, Lesley A
Publicado em 2013

Sofosbuvir as a drug in recurrent HCV therapy occurring after liver transplantation

Por Katarzyna Lipa, Magdalena Julia Jabłońska, Patryk Kaczor, Kamil Leis, Krystian Kałużny, Przemysław Gałązka
Publicado em 2018-09-01

Variation in dose and plasma level of lamotrigine in patients discharged from a mental health trust

Por Douglas-Hall, Petrina, Dzahini, Olubanke, Gaughran, Fiona, Bile, Ahmed, Taylor, David
Publicado no Ther Adv Psychopharmacol (2016)

Slow-, Tight-Binding Inhibition of CYP17A1 by Abiraterone Redefines Its Kinetic Selectivity and Dosing Regimen

Por Cheong, Eleanor Jing Yi, Nair, Pramod C., Neo, Rebecca Wan Yi, Tu, Ho Thanh, Lin, Fu, Chiong, Edmund, Esuvaranathan, Kesavan, Fan, Hao, Szmulewitz, Russell Z., Peer, Cody J., Figg, William D., Chai, Christina Li Lin, Miners, John O., Chan, Eric Chun Yong
Publicado no J Pharmacol Exp Ther (2020)

The effect of liver microsomal enzyme inducing and inhibiting drugs on insulin mediated glucose metabolism in man.

Por Lahtela, J T, Gachalyi, B, Eksymä, S, Hämäläinen, A, Sotaniemi, E A
Publicado em 1986

Single Dose of a Polyanhydride Particle-Based Vaccine Generates Potent Antigen-Specific Antitumor Immune Responses

Por Wafa, Emad I., Geary, Sean M., Ross, Kathleen A., Goodman, Jonathan T., Narasimhan, Balaji, Salem, Aliasger K.
Publicado no J Pharmacol Exp Ther (2019)

The effects of different doses of atorvastatin on serum lipid profile, glycemic control, and liver enzymes in patients with ischemic cerebrovascular accident

Por Sadeghi, Roxana, Asadpour-Piranfar, Mohammad, Asadollahi, Marjan, Taherkhani, Maryam, Baseri, Fariba
Publicado no ARYA Atheroscler (2014)

Super-compact treatment with a high dose of moxifloxacin in patients with drug-resistant tuberculosis and its resistance mechanisms

Por WANG, QINGJIANG, ZHANG, CHUNXIAO, GUO, JINHUI, HUANG, JIAN, XI, XIUE, ZHANG, LIGONG, CUI, XIUQIN
Publicado no Exp Ther Med (2015)

Molecular Pharmacodynamics-Guided Scheduling of Biologically Effective Doses: A Drug Development Paradigm Applied to MET Tyrosine Kinase Inhibitors

Por Srivastava, Apurva K., Hollingshead, Melinda G., Govindharajulu, Jeevan P., Covey, Joseph M., Liston, Dane, Simpson, Melanie A., Peggins, James O., Bottaro, Donald P., Wright, John J., Kinders, Robert J., Doroshow, James H., Parchment, Ralph E.
Publicado no Mol Cancer Ther (2018)

Increased levels of urinary phenylacetylglycine associated with mitochondrial toxicity in a model of drug-induced phospholipidosis

Por Doessegger, Lucette, Schmitt, Georg, Lenz, Barbara, Fischer, Holger, Schlotterbeck, Götz, Atzpodien, Elke-Astrid, Senn, Hans, Suter, Laura, Csato, Miklos, Evers, Stefan, Singer, Thomas
Publicado em 2013

Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription

Por PARK, WOO-JAE, KIM, SO-YEON, KIM, YE-RYUNG, PARK, JOO-WON
Publicado no Int J Mol Med (2016)

Effect of varying doses of tamoxifen on ovarian histopathology, serum VEGF, and endothelin 1 levels in ovarian hyperstimulation syndrome: an experimental study

Por Pala, Şehmus, Atilgan, Remzi, Ozkan¹, Zehra Sema, Kavak, Salih Burçin, Ilhan, Nevin, Akpolat, Nusret, Sapmaz, Ekrem
Publicado no Drug Des Devel Ther (2015)

Optimizing clopidogrel dose response: a new clinical algorithm comprising CYP2C19 pharmacogenetics and drug interactions

Por Saab, Yolande B, Zeenny, Rony, Ramadan, Wijdan H
Publicado no Ther Clin Risk Manag (2015)

Repeated Administration of a Mutant Cocaine Esterase: Effects on Plasma Cocaine Levels, Cocaine...

Por Collins, Gregory T., Brim, Remy L., Noon, Kathleen R., Narasimhan, Diwahar, Lukacs, Nicholas W., Sunahara, Roger K., Woods, James H., Ko, Mei-Chuan
Publicado em 2012

The Approved Dose of Ivermectin Alone is not the Ideal Dose for the Treatment of COVID‐19

Por Schmith, Virginia D., Zhou, Jie (Jessie), Lohmer, Lauren R.L.
Publicado no Clin Pharmacol Ther (2020)