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The Approved Dose of Ivermectin Alone is not the Ideal Dose for the Treatment of COVID‐19

Caly et al.(1) reported that ivermectin inhibited severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) in vitro for up to 48 hours using ivermectin at 5 μM. The concentration resulting in 50% inhibition (IC(50); 2 µM) was > 35× higher than the maximum plasma concentration (C(max)) after o...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Schmith, Virginia D., Zhou, Jie (Jessie), Lohmer, Lauren R.L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267287/
https://ncbi.nlm.nih.gov/pubmed/32378737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1889
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