Relationship between Dose, Drug Levels, and D2 Receptor Occupancy for the Atypical Antipsychotics Risperidone and Paliperidone

Por Muly, E. C., Votaw, J. R., Ritchie, J., Howell, L. L.
Publicado em 2012

Clozapine-Related EEG Changes and Seizures: Dose and Plasma-Level Relationships

Por Varma, Seema, Bishara, Delia, Besag, Frank M. C., Taylor, David
Publicado em 2011

Drug-drug interaction between isavuconazole and tacrolimus: a case report indicating the need for tacrolimus drug-level monitoring

Por Kim, Tiffany, Jancel, Timothy, Kumar, Parag, Freeman, Alexandra F.
Publicado no J Clin Pharm Ther (2015)

Use of glomerular filtration rate estimating equations for drug dosing in HIV-positive patients

Por Okparavero, Aghogho A, Tighiouart, Hocine, Krishnasami, Zipporah, Wyatt, Christina M, Graham, Hiba, Hellinger, James, Inker, Lesley A
Publicado em 2013

Identification of Granulocyte Colony-Stimulating Factor and Interleukin-6 as Candidate Biomarkers of CBLB502 Efficacy as a Medical Radiation Countermeasure

Por Krivokrysenko, Vadim I., Shakhov, Alexander N., Singh, Vijay K., Bone, Frederick, Kononov, Yevgeniy, Shyshynova, Inna, Cheney, Alec, Maitra, Ratan K., Purmal, Andrei, Whitnall, Mark H., Gudkov, Andrei V., Feinstein, Elena
Publicado em 2012

Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro

Por Neumann, Susanne, Eliseeva, Elena, Boutin, Alisa, Barnaeva, Elena, Ferrer, Marc, Southall, Noel, Kim, David, Hu, Xin, Morgan, Sarah J., Marugan, Juan J., Gershengorn, Marvin C.
Publicado no J Pharmacol Exp Ther (2018)

Variation in dose and plasma level of lamotrigine in patients discharged from a mental health trust

Por Douglas-Hall, Petrina, Dzahini, Olubanke, Gaughran, Fiona, Bile, Ahmed, Taylor, David
Publicado no Ther Adv Psychopharmacol (2016)

Drug design with Cdc7 kinase: a potential novel cancer therapy target

Por Sawa, Masaaki, Masai, Hisao
Publicado em 2009

Super-compact treatment with a high dose of moxifloxacin in patients with drug-resistant tuberculosis and its resistance mechanisms

Por WANG, QINGJIANG, ZHANG, CHUNXIAO, GUO, JINHUI, HUANG, JIAN, XI, XIUE, ZHANG, LIGONG, CUI, XIUQIN
Publicado no Exp Ther Med (2015)

Increased levels of urinary phenylacetylglycine associated with mitochondrial toxicity in a model of drug-induced phospholipidosis

Por Doessegger, Lucette, Schmitt, Georg, Lenz, Barbara, Fischer, Holger, Schlotterbeck, Götz, Atzpodien, Elke-Astrid, Senn, Hans, Suter, Laura, Csato, Miklos, Evers, Stefan, Singer, Thomas
Publicado em 2013

Impact of low-dose prednisolone on bone synthesis and resorption in early rheumatoid arthritis: experiences from a two-year randomized study

Por Engvall, Inga-Lill, Svensson, Björn, Tengstrand, Birgitta, Brismar, Kerstin, Hafström, Ingiäld
Publicado em 2008

Repeated Administration of a Mutant Cocaine Esterase: Effects on Plasma Cocaine Levels, Cocaine...

Por Collins, Gregory T., Brim, Remy L., Noon, Kathleen R., Narasimhan, Diwahar, Lukacs, Nicholas W., Sunahara, Roger K., Woods, James H., Ko, Mei-Chuan
Publicado em 2012

Molecular Pharmacodynamics-Guided Scheduling of Biologically Effective Doses: A Drug Development Paradigm Applied to MET Tyrosine Kinase Inhibitors

Por Srivastava, Apurva K., Hollingshead, Melinda G., Govindharajulu, Jeevan P., Covey, Joseph M., Liston, Dane, Simpson, Melanie A., Peggins, James O., Bottaro, Donald P., Wright, John J., Kinders, Robert J., Doroshow, James H., Parchment, Ralph E.
Publicado no Mol Cancer Ther (2018)

Effect of varying doses of tamoxifen on ovarian histopathology, serum VEGF, and endothelin 1 levels in ovarian hyperstimulation syndrome: an experimental study

Por Pala, Şehmus, Atilgan, Remzi, Ozkan¹, Zehra Sema, Kavak, Salih Burçin, Ilhan, Nevin, Akpolat, Nusret, Sapmaz, Ekrem
Publicado no Drug Des Devel Ther (2015)

Optimizing clopidogrel dose response: a new clinical algorithm comprising CYP2C19 pharmacogenetics and drug interactions

Por Saab, Yolande B, Zeenny, Rony, Ramadan, Wijdan H
Publicado no Ther Clin Risk Manag (2015)

Type I Interferon Receptor is a Primary Regulator of Target-Mediated Drug Disposition of Interferon-β in Mice

Por Abraham, Anson K., Kagan, Leonid, Kumar, Sarmishtha, Mager, Donald E.
Publicado em 2010

Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance

Por Bewry, Nadine N., Nair, Rajesh R., Emmons, Michael F., Boulware, David, Pinilla-Ibarz, Javier, Hazlehurst, Lori A.
Publicado em 2008

Molecular diagnostics of a single drug-resistant multiple myeloma case using targeted next-generation sequencing

Por Ikeda, Hiroshi, Ishiguro, Kazuya, Igarashi, Tetsuyuki, Aoki, Yuka, Hayashi, Toshiaki, Ishida, Tadao, Sasaki, Yasushi, Tokino, Takashi, Shinomura, Yasuhisa
Publicado no Onco Targets Ther (2015)

Effectiveness of thiazides on serum and urinary calcium levels and bone mineral density in patients with osteoporosis: a systematic review and meta-analysis

Por Cheng, Lei, Zhang, Keyan, Zhang, Zhenyong
Publicado no Drug Des Devel Ther (2018)

Time and dose relationships between schisandrin B- and schisandrae fructus oil-induced...

Por Zhang, Yi, Pan, Si-Yuan, Zhou, Shu-Feng, Wang, Xiao-Yan, Sun, Nan, Zhu, Pei-Li, Chu, Zhu-Sheng, Yu, Zhi-Ling, Ko, Kam-Ming
Publicado em 2014