Identification of Granulocyte Colony-Stimulating Factor and Interleukin-6 as Candidate Biomarkers of CBLB502 Efficacy as a Medical Radiation Countermeasure

Given an ever-increasing risk of nuclear and radiological emergencies, there is a critical need for development of medical radiation countermeasures (MRCs) that are safe, easily administered, and effective in preventing and/or mitigating the potentially lethal tissue damage caused by acute high-dose...

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Detalhes bibliográficos
Main Authors: Krivokrysenko, Vadim I., Shakhov, Alexander N., Singh, Vijay K., Bone, Frederick, Kononov, Yevgeniy, Shyshynova, Inna, Cheney, Alec, Maitra, Ratan K., Purmal, Andrei, Whitnall, Mark H., Gudkov, Andrei V., Feinstein, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Drug Discovery and Translational Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477210/
https://ncbi.nlm.nih.gov/pubmed/22837010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.196071
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