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The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates

There are currently no approved medical radiation countermeasures (MRC) to reduce the lethality of high-dose total body ionizing irradiation expected in nuclear emergencies. An ideal MRC would be effective even when administered well after radiation exposure and would counteract the effects of irrad...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Krivokrysenko, Vadim I., Toshkov, Ilia A., Gleiberman, Anatoli S., Krasnov, Peter, Shyshynova, Inna, Bespalov, Ivan, Maitra, Ratan K., Narizhneva, Natalya V., Singh, Vijay K., Whitnall, Mark H., Purmal, Andrei A., Shakhov, Alexander N., Gudkov, Andrei V., Feinstein, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569586/
https://ncbi.nlm.nih.gov/pubmed/26367124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135388
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