Resultados da pesquisa - (( drug de deberes ther ) OR ((( drug doses level ther ) OR ( drug dose levels ther ))))

1

Relationship between Dose, Drug Levels, and D2 Receptor Occupancy for the Atypical Antipsychotics Risperidone and Paliperidone

Por Muly, E. C., Votaw, J. R., Ritchie, J., Howell, L. L.
Publicado em 2012

“... and was related to serum and cerebrospinal fluid drug levels. Repeated 2-week treatment with risperidone...”
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2

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Strategies to conserve salbutamol pressurized metered-dose inhaler stock levels amid COVID-19 drug shortage

Por Elbeddini, Ali, Tayefehchamani, Yasamin, Yang, Lucy
Publicado no Drugs Ther Perspect (2020)

“... of salbutamol pressurized metered-dose inhalers (pMDIs), as well as salbutamol Diskus, leading to a decline...”
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3

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Clozapine-Related EEG Changes and Seizures: Dose and Plasma-Level Relationships

Por Varma, Seema, Bishara, Delia, Besag, Frank M. C., Taylor, David
Publicado em 2011

“... clozapine dose or level, or only as remedial treatment. In this review, we examine the relevant literature...”
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Proof of Concept: Drug Selection? Or Dose Selection? Thoughts on Multiplicity Issues

Por Li, Qian H., Deng, Qiqi, Ting, Naitee
Publicado no Ther Innov Regul Sci (2021)

“... doses or drugs are included in one PoC study. In such discussion, one fundamental question of applying...”
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Drug-drug interaction between isavuconazole and tacrolimus: a case report indicating the need for tacrolimus drug-level monitoring

Por Kim, Tiffany, Jancel, Timothy, Kumar, Parag, Freeman, Alexandra F.
Publicado no J Clin Pharm Ther (2015)

“... isavuconazole and tacrolimus there are no recommendations on dose-adjustment when these drugs are given...”
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Use of glomerular filtration rate estimating equations for drug dosing in HIV-positive patients

Por Okparavero, Aghogho A, Tighiouart, Hocine, Krishnasami, Zipporah, Wyatt, Christina M, Graham, Hiba, Hellinger, James, Inker, Lesley A
Publicado em 2013

“... antiretroviral drug dosing for level of kidney function in 200 HIV-positive patients on stable antiretroviral...”
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Variation in dose and plasma level of lamotrigine in patients discharged from a mental health trust

Por Douglas-Hall, Petrina, Dzahini, Olubanke, Gaughran, Fiona, Bile, Ahmed, Taylor, David
Publicado no Ther Adv Psychopharmacol (2016)

“... and smoking status had no significant effect on dose or plasma levels. Patients taking an enzyme-inducing drug...”
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Slow-, Tight-Binding Inhibition of CYP17A1 by Abiraterone Redefines Its Kinetic Selectivity and Dosing Regimen

Por Cheong, Eleanor Jing Yi, Nair, Pramod C., Neo, Rebecca Wan Yi, Tu, Ho Thanh, Lin, Fu, Chiong, Edmund, Esuvaranathan, Kesavan, Fan, Hao, Szmulewitz, Russell Z., Peer, Cody J., Figg, William D., Chai, Christina Li Lin, Miners, John O., Chan, Eric Chun Yong
Publicado no J Pharmacol Exp Ther (2020)

Assuntos: “...Drug Discovery and Translational Medicine...”
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Single Dose of a Polyanhydride Particle-Based Vaccine Generates Potent Antigen-Specific Antitumor Immune Responses

Por Wafa, Emad I., Geary, Sean M., Ross, Kathleen A., Goodman, Jonathan T., Narasimhan, Balaji, Salem, Aliasger K.
Publicado no J Pharmacol Exp Ther (2019)

Assuntos: “...Special Issue on Drug Delivery Technologies...”
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Super-compact treatment with a high dose of moxifloxacin in patients with drug-resistant tuberculosis and its resistance mechanisms

Por WANG, QINGJIANG, ZHANG, CHUNXIAO, GUO, JINHUI, HUANG, JIAN, XI, XIUE, ZHANG, LIGONG, CUI, XIUQIN
Publicado no Exp Ther Med (2015)

“...The aim of this study was to investigate the curative effect and resistance mechanisms of high-dose...”
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Increased levels of urinary phenylacetylglycine associated with mitochondrial toxicity in a model of drug-induced phospholipidosis

Por Doessegger, Lucette, Schmitt, Georg, Lenz, Barbara, Fischer, Holger, Schlotterbeck, Götz, Atzpodien, Elke-Astrid, Senn, Hans, Suter, Laura, Csato, Miklos, Evers, Stefan, Singer, Thomas
Publicado em 2013

“... amphiphilic drugs. However, drug-induced PLD is reversible. Evidence of PLD from animal studies with some...”
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Effect of varying doses of tamoxifen on ovarian histopathology, serum VEGF, and endothelin 1 levels in ovarian hyperstimulation syndrome: an experimental study

Por Pala, Şehmus, Atilgan, Remzi, Ozkan¹, Zehra Sema, Kavak, Salih Burçin, Ilhan, Nevin, Akpolat, Nusret, Sapmaz, Ekrem
Publicado no Drug Des Devel Ther (2015)

“...). CONCLUSION: Tamoxifen 1 g and 3 g resulted in a dose-dependent increase in VEGF and endothelin 1 levels...”
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Molecular Pharmacodynamics-Guided Scheduling of Biologically Effective Doses: A Drug Development Paradigm Applied to MET Tyrosine Kinase Inhibitors

Por Srivastava, Apurva K., Hollingshead, Melinda G., Govindharajulu, Jeevan P., Covey, Joseph M., Liston, Dane, Simpson, Melanie A., Peggins, James O., Bottaro, Donald P., Wright, John J., Kinders, Robert J., Doroshow, James H., Parchment, Ralph E.
Publicado no Mol Cancer Ther (2018)

“...) markers to identify “biologically effective doses” (BEDs) below maximum tolerable doses, yet...”
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Optimizing clopidogrel dose response: a new clinical algorithm comprising CYP2C19 pharmacogenetics and drug interactions

Por Saab, Yolande B, Zeenny, Rony, Ramadan, Wijdan H
Publicado no Ther Clin Risk Manag (2015)

“... reduced function of the gene variant of the CYP2C19 has been associated with lower drug metabolite levels...”
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Repeated Administration of a Mutant Cocaine Esterase: Effects on Plasma Cocaine Levels, Cocaine...

Por Collins, Gregory T., Brim, Remy L., Noon, Kathleen R., Narasimhan, Diwahar, Lukacs, Nicholas W., Sunahara, Roger K., Woods, James H., Ko, Mei-Chuan
Publicado em 2012

Assuntos: “...Drug Discovery and Translational Medicine...”
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The Approved Dose of Ivermectin Alone is not the Ideal Dose for the Treatment of COVID‐19

Por Schmith, Virginia D., Zhou, Jie (Jessie), Lohmer, Lauren R.L.
Publicado no Clin Pharmacol Ther (2020)

“... the IC(50), even for a dose level 10× higher than the approved dose. Even with the high lung:plasma ratio...”
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Time and dose relationships between schisandrin B- and schisandrae fructus oil-induced...

Por Zhang, Yi, Pan, Si-Yuan, Zhou, Shu-Feng, Wang, Xiao-Yan, Sun, Nan, Zhu, Pei-Li, Chu, Zhu-Sheng, Yu, Zhi-Ling, Ko, Kam-Ming
Publicado em 2014

“... fructus (SF). This study was conducted to compare the time- and dose-response between Sch B- and SF oil...”
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A comparison of adeB gene expression levels under conditions of induced resistance by different drugs in vitro in Acinetobacter baumannii

Por Zhu, Wan, Wang, Hui, Zhang, Jing-Ping
Publicado no Exp Ther Med (2017)

“... was confirmed with the three drugs. The expression level of the adeB was determined by quantitative polymerase...”
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Evaluating the Role of Genetic Variants on first‐line antiepileptic drug response in North India: Significance of SCN1A and GABRA1 Gene Variants in Phenytoin Monotherapy and its Serum Drug Levels

Por Baghel, Ruchi, Grover, Sandeep, Kaur, Harpreet, Jajodia, Ajay, Rawat, Chitra, Srivastava, Ankit, Kushwaha, Suman, Agarwal, Rachna, Sharma, Sangeeta, Kukreti, Ritushree
Publicado no CNS Neurosci Ther (2016)

“... with drug response, dose levels, and drug levels in 408 patients with epilepsy. RESULTS: Both GABRA1 and SCN...”
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High-dose atorvastatin versus moderate dose on early vascular protection after ST-elevation myocardial infarction

Por Gavazzoni, Mara, Gorga, Elio, Derosa, Giuseppe, Maffioli, Pamela, Metra, Marco, Raddino, Riccardo
Publicado no Drug Des Devel Ther (2017)

“...BACKGROUND AND AIM: Clinical benefits of early high-dose statin therapy after acute coronary...”
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