Resultados da pesquisa - (( _ nat comp can non ) OR ((( _ dna clamp can non ) OR ( j art congo cas ngo ))))

1

The Escherichia coli Clamp Loader Can Actively Pry Open the β-Sliding Clamp

Por Paschall, Christopher O., Thompson, Jennifer A., Marzahn, Melissa R., Chiraniya, Ankita, Hayner, Jaclyn N., O'Donnell, Mike, Robbins, Arthur H., McKenna, Robert, Bloom, Linda B.
Publicado em 2011

Assuntos: “...DNA and Chromosomes...”
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2

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Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp

Por Fujisawa, Ryo, Ohashi, Eiji, Hirota, Kouji, Tsurimoto, Toshiki
Publicado no Nucleic Acids Res (2017)

“... its interaction with Polε, and can load PCNA onto DNA when Polε is not in DNA synthesis mode...”
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3

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Reverse transcriptases can clamp together nucleic acids strands with two complementary bases at their 3′-termini for initiating DNA synthesis

Por Oz-Gleenberg, Iris, Herschhorn, Alon, Hizi, Amnon
Publicado em 2011

“... one C or G. This RT-induced strand ‘clamping’ activity promotes RT-directed DNA synthesis...”
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4

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Dynamics of DNA-tracking by two sliding-clamp proteins.

Por Fu, T J, Sanders, G M, O'Donnell, M, Geiduschek, E P
Publicado em 1996

“...Bacteriophage T4 gene 45 protein (gp45) and Escherichia coli beta are DNA-tracking sliding-clamp...”
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5

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i-Clamp phenoxazine for the fine tuning of DNA i-motif stability

Por Tsvetkov, Vladimir B, Zatsepin, Timofei S, Belyaev, Evgeny S, Kostyukevich, Yury I, Shpakovski, George V, Podgorsky, Victor V, Pozmogova, Galina E, Varizhuk, Anna M, Aralov, Andrey V
Publicado no Nucleic Acids Res (2018)

“...Non-canonical DNA structures are widely used for regulation of gene expression, in DNA...”
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6

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Conserved residues in the δ subunit help the E. coli clamp loader, γ complex, target primer-template DNA for clamp assembly

Por Chen, Siying, Coman, Maria Magdalena, Sakato, Miho, O’Donnell, Michael, Hingorani, Manju M.
Publicado em 2008

“... that dsDNA, not ssDNA, can trigger a burst of ATP hydrolysis by γ complex and clamp assembly, but only at far...”
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7

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PNA clamping-assisted fluorescence melting curve analysis for detecting EGFR and KRAS mutations in the circulating tumor DNA of patients with advanced non-small cell lung cancer

Por Han, Ji-Youn, Choi, Jae-Jin, Kim, Jin Young, Han, You Lim, Lee, Geon Kook
Publicado no BMC Cancer (2016)

“...)-based method for analyzing EGFR and KRAS mutations in the plasma cfDNA of patients with advanced non...”
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8

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Data on the target search by a single protein on DNA measured with ultrafast force-clamp spectroscopy

Por Carina Monico, Alessia Tempestini, Lucia Gardini, Francesco Saverio Pavone, Marco Capitanio
Publicado em 2019-06-01

“... to few tens of base pairs amongst the millions of non-specific chromosomal DNA has been puzzling...”
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9

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An artificial processivity clamp made with streptavidin facilitates oriented attachment of polymerase–DNA complexes to surfaces

Por Williams, John G. K., Steffens, David L., Anderson, Jon P., Urlacher, Teresa M., Lamb, Donald T., Grone, Daniel L., Egelhoff, Jolene C.
Publicado em 2008

“...-formed polymerase–DNA–streptavidin complexes can be stored frozen and subsequently thawed without...”
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10

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Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair

Por Liu, Jiaquan, Hanne, Jeungphill, Britton, Brooke M., Bennett, Jared, Kim, Daehyung, Lee, Jong-Bong, Fishel, Richard
Publicado no Nature (2016)

“...) homologues initiate mismatch repair and, in higher eukaryotes, act as DNA damage sensors that can trigger...”
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11

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Using stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation

Por Groothuizen, Flora S., Fish, Alexander, Petoukhov, Maxim V., Reumer, Annet, Manelyte, Laura, Winterwerp, Herrie H. K., Marinus, Martin G., Lebbink, Joyce H. G., Svergun, Dmitri I., Friedhoff, Peter, Sixma, Titia K.
Publicado em 2013

“..., resulting in mostly extended structures. Tetrameric MutS has a slow dissociation from DNA, which can be due...”
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12

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EGFR Mutation Analysis of Circulating Tumor DNA Using an Improved PNA-LNA PCR Clamp Method

Por Watanabe, Kana, Fukuhara, Tatsuro, Tsukita, Yoko, Morita, Mami, Suzuki, Aya, Tanaka, Nobuyuki, Terasaki, Hiroshi, Nukiwa, Toshihiro, Maemondo, Makoto
Publicado no Can Respir J (2016)

“...Introduction. Rebiopsies have become more crucial in non-small cell lung cancer (NSCLC). Instead...”
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13

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Evolutionary clues to eukaryotic DNA clamp-loading mechanisms: analysis of the functional constraints imposed on replication factor C AAA+ ATPases

Por Neuwald, Andrew F.
Publicado em 2005

“... to conformational changes that can load the clamp onto DNA. While these questions can, of course, only be resolved...”
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14

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The phosphate clamp: a small and independent motif for nucleic acid backbone recognition

Por Komeda, Seiji, Moulaei, Tinoush, Chikuma, Masahiko, Odani, Akira, Kipping, Ralph, Farrell, Nicholas P., Williams, Loren Dean
Publicado em 2011

“...The 1.7 Å X-ray crystal structure of the B-DNA dodecamer, [d(CGCGAATTCGCG)](2) (DDD)-bound non...”
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15

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The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic...

Por Gembka, Agnieszka, Toueille, Magali, Smirnova, Ekaterina, Poltz, Rainer, Ferrari, Elena, Villani, Giuseppe, Hübscher, Ulrich
Publicado em 2007

“... functions in DNA damage sensing and signaling pathways, plays also a direct role in various DNA repair...”
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16

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An N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor Mfd

Por Murphy, Michael N., Gong, Peng, Ralto, Kenneth, Manelyte, Laura, Savery, Nigel J., Theis, Karsten
Publicado em 2009

“.... In transcription-coupled DNA repair, motor activity serves to remove RNA polymerase stalled on damaged DNA, making...”
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17

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DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation

Por Guha, Minakshi, Castellanos-Rizaldos, Elena, Makrigiorgos, G. Mike
Publicado em 2013

“... T790M EGFR mutations from target DNA prior to implementing PNA-LNA PCR, a method that can detect 1...”
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18

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The phosphate clamp: sequence selective nucleic acid binding profiles and conformational induction of endonuclease inhibition by cationic Triplatin complexes

Por Prisecaru, Andreea, Molphy, Zara, Kipping, Ralph G., Peterson, Erica J., Qu, Yun, Kellett, Andrew, Farrell, Nicholas P.
Publicado no Nucleic Acids Res (2014)

“... (AH78 TriplatinNC) and 7 (AH78H), are potent non-covalent DNA binding agents where nucleic acid...”
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19

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Snapback Primer Mediated Clamping PCR for Detection of EGFR and KRAS Mutations in NSCLC Patients by High Resolution Melting Analysis

Por Sun, Haiyan, Yang, Yang, Yang, Lixin, Su, Bo, Jiang, Gening, Fei, Ke, Lu, Daru
Publicado em 2014

“... mutant samples can be diagnosed. And finally, in a double-blind experiment of 150 cases of non-small-cell...”
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20

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Recruitment of DNA repair synthesis machinery to sites of DNA damage/repair in living human cells

Por Hashiguchi, Kazunari, Matsumoto, Yoshihiro, Yasui, Akira
Publicado em 2007

“...The eukaryotic sliding DNA clamp, proliferating cell nuclear antigen (PCNA), is essential for DNA...”
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