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Recruitment of DNA repair synthesis machinery to sites of DNA damage/repair in living human cells

The eukaryotic sliding DNA clamp, proliferating cell nuclear antigen (PCNA), is essential for DNA replication and repair synthesis. In order to load the ring-shaped, homotrimeric PCNA onto the DNA double helix, the ATPase activity of the replication factor C (RFC) clamp loader complex is required. A...

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Autors principals: Hashiguchi, Kazunari, Matsumoto, Yoshihiro, Yasui, Akira
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888830/
https://ncbi.nlm.nih.gov/pubmed/17439963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm115
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