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Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage
At sites of chronic inflammation, epithelial cells are exposed to high levels of reactive oxygen species and undergo cancer-associated DNA methylation changes, suggesting that inflammation may initiate epigenetic alterations. Previously, we demonstrated that oxidative damage causes epigenetic silenc...
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| Pubblicato in: | J Mol Cell Biol |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4937888/ https://ncbi.nlm.nih.gov/pubmed/26186941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjv050 |
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