Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage

At sites of chronic inflammation, epithelial cells are exposed to high levels of reactive oxygen species and undergo cancer-associated DNA methylation changes, suggesting that inflammation may initiate epigenetic alterations. Previously, we demonstrated that oxidative damage causes epigenetic silenc...

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Vydáno v:J Mol Cell Biol
Hlavní autoři: Ding, Ning, Bonham, Emily M., Hannon, Brooke E., Amick, Thomas R., Baylin, Stephen B., O'Hagan, Heather M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937888/
https://ncbi.nlm.nih.gov/pubmed/26186941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjv050
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