The Escherichia coli Clamp Loader Can Actively Pry Open the β-Sliding Clamp

Clamp loaders load ring-shaped sliding clamps onto DNA. Once loaded onto DNA, sliding clamps bind to DNA polymerases to increase the processivity of DNA synthesis. To load clamps onto DNA, an open clamp loader-clamp complex must form. An unresolved question is whether clamp loaders capture clamps th...

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Main Authors: Paschall, Christopher O., Thompson, Jennifer A., Marzahn, Melissa R., Chiraniya, Ankita, Hayner, Jaclyn N., O'Donnell, Mike, Robbins, Arthur H., McKenna, Robert, Bloom, Linda B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
DNA and Chromosomes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234947/
https://ncbi.nlm.nih.gov/pubmed/21971175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.268169
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