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The ATP Sites of AAA+ Clamp Loaders Work Together as a Switch to Assemble Clamps on DNA

Clamp loaders belong to a family of proteins known as ATPases associated with various cellular activities (AAA+). These proteins utilize the energy from ATP binding and hydrolysis to perform cellular functions. The clamp loader is required to load the clamp onto DNA for use by DNA polymerases to inc...

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Detalhes bibliográficos
Main Authors: Marzahn, Melissa R., Hayner, Jaclyn N., Finkelstein, Jeff, O'Donnell, Mike, Bloom, Linda B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937632/
https://ncbi.nlm.nih.gov/pubmed/24436332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541466
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