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The Clamp Loader Assembles the β Clamp onto Either a 3′ or 5′ Primer Terminus: THE UNDERLYING BASIS FAVORING 3′ LOADING
Clamp loaders assemble sliding clamps onto 3′ primed sites for DNA polymerases. Clamp loaders are thought to be specific for a 3′ primed site, and unable to bind a 5′ site. We demonstrate here that the Escherichia coli γ complex clamp loader can load the β clamp onto a 5′ primed site, although with...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781543/ https://ncbi.nlm.nih.gov/pubmed/19759020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050310 |
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