The Clamp Loader Assembles the β Clamp onto Either a 3′ or 5′ Primer Terminus: THE UNDERLYING BASIS FAVORING 3′ LOADING

Eitemau Tebyg

• A Slow ATP-induced Conformational Change Limits the Rate of DNA Binding but Not the Rate of β Clamp Binding by the Escherichia coli γ Complex Clamp Loader
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• The ATP Sites of AAA+ Clamp Loaders Work Together as a Switch to Assemble Clamps on DNA
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• The RFC Clamp Loader: Structure and Function
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