Replication Factor C Is a More Effective Proliferating Cell Nuclear Antigen (PCNA) Opener than the Checkpoint Clamp Loader, Rad24-RFC

Clamp loaders from all domains of life load clamps onto DNA. The clamp tethers DNA polymerases to DNA to increase the processivity of synthesis as well as the efficiency of replication. Here, we investigated proliferating cell nuclear antigen (PCNA) binding and opening by the Saccharomyces cerevisia...

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Bibliographic Details
Main Authors: Thompson, Jennifer A., Marzahn, Melissa R., O'Donnell, Mike, Bloom, Linda B.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
DNA and Chromosomes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265898/
https://ncbi.nlm.nih.gov/pubmed/22115746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.318899
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