Site-specific protein modification to identify the MutL interface of MutH

Por Toedt, Grischa H., Krishnan, Ravi, Friedhoff, Peter
Publicado em 2003

Maintaining a sense of direction during long-range communication on DNA

Por Szczelkun, Mark D., Friedhoff, Peter, Seidel, Ralf
Publicado em 2010

Structural and functional analysis of the MutS C-terminal tetramerization domain

Por Manelyte, Laura, Urbanke, Claus, Giron-Monzon, Luis, Friedhoff, Peter
Publicado em 2006

Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeats

Por Gabsalilow, Lilia, Schierling, Benno, Friedhoff, Peter, Pingoud, Alfred, Wende, Wolfgang
Publicado em 2013

Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair

Por Kosinski, Jan, Hinrichsen, Inga, Bujnicki, Janusz M., Friedhoff, Peter, Plotz, Guido
Publicado em 2010

The C-Terminal Domain of the MutL Homolog from Neisseria gonorrhoeae Forms an Inverted Homodimer

Por Namadurai, Sivakumar, Jain, Deepti, Kulkarni, Dhananjay S., Tabib, Chaitanya R., Friedhoff, Peter, Rao, Desirazu N., Nair, Deepak T.
Publicado em 2010

Identifying an interaction site between MutH and the C-terminal domain of MutL by crosslinking, affinity purification, chemical coding and mass spectrometry

Por Ahrends, Robert, Kosinski, Jan, Kirsch, Dieter, Manelyte, Laura, Giron-Monzon, Luis, Hummerich, Lars, Schulz, Oliver, Spengler, Bernhard, Friedhoff, Peter
Publicado em 2006

Is Thymidine Glycol Containing DNA a Substrate of E. coli DNA Mismatch Repair System?

Por Perevozchikova, Svetlana A., Trikin, Roman M., Heinze, Roger J., Romanova, Elena A., Oretskaya, Tatiana S., Friedhoff, Peter, Kubareva, Elena A.
Publicado em 2014

Physical and functional interactions between Escherichia coli MutL and the Vsr repair endonuclease

Por Heinze, Roger J., Giron-Monzon, Luis, Solovyova, Alexandra, Elliot, Sarah L., Geisler, Sven, Cupples, Claire G., Connolly, Bernard A., Friedhoff, Peter
Publicado em 2009

Chemical Trapping of the Dynamic MutS-MutL Complex Formed in DNA Mismatch Repair in Escherichia coli

Por Winkler, Ines, Marx, Andreas D., Lariviere, Damien, Heinze, Roger J., Cristovao, Michele, Reumer, Annet, Curth, Ute, Sixma, Titia K., Friedhoff, Peter
Publicado em 2011

Mutations in the MutSα interaction interface of MLH1 can abolish DNA mismatch repair

Por Plotz, Guido, Welsch, Christoph, Giron-Monzon, Luis, Friedhoff, Peter, Albrecht, Mario, Piiper, Albrecht, Biondi, Ricardo M., Lengauer, Thomas, Zeuzem, Stefan, Raedle, Jochen
Publicado em 2006

Single-molecule multiparameter fluorescence spectroscopy reveals directional MutS binding to mismatched bases in DNA

Por Cristóvão, Michele, Sisamakis, Evangelos, Hingorani, Manju M., Marx, Andreas D., Jung, Caroline P., Rothwell, Paul J., Seidel, Claus A. M., Friedhoff, Peter
Publicado em 2012

Chemical trapping of the dynamic MutS-MutL complex formed in DNA mismatch repair in Escherichia coli.

Por Winkler, Ines, Marx, Andreas D., Lariviere, Damien, Manelyte, Laura, Giron-Monzon, Luis, Heinze, Roger J., Cristovao, Michele, Reumer, Annet, Curth, Ute, Sixma, Titia K., Friedhoff, Peter
Publicado em 2011

Structure of the endonuclease domain of MutL: unlicensed to cut

Por Pillon, Monica C., Lorenowicz, Jessica J., Uckelmann, Michael, Klocko, Andrew D., Mitchell, Ryan R., Chung, Yu Seon, Modrich, Paul, Walker, Graham C., Simmons, Lyle A., Friedhoff, Peter, Guarné, Alba
Publicado em 2010

Using stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation

Por Groothuizen, Flora S., Fish, Alexander, Petoukhov, Maxim V., Reumer, Annet, Manelyte, Laura, Winterwerp, Herrie H. K., Marinus, Martin G., Lebbink, Joyce H. G., Svergun, Dmitri I., Friedhoff, Peter, Sixma, Titia K.
Publicado em 2013

Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair

Por Hermans, Nicolaas, Laffeber, Charlie, Cristovão, Michele, Artola-Borán, Mariela, Mardenborough, Yannicka, Ikpa, Pauline, Jaddoe, Aruna, Winterwerp, Herrie H.K., Wyman, Claire, Jiricny, Josef, Kanaar, Roland, Friedhoff, Peter, Lebbink, Joyce H.G.
Publicado no Nucleic Acids Res (2016)

Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3

Por Schneider, Tim, Hung, Lee-Hsueh, Aziz, Masood, Wilmen, Anna, Thaum, Stephanie, Wagner, Jacqueline, Janowski, Robert, Müller, Simon, Schreiner, Silke, Friedhoff, Peter, Hüttelmaier, Stefan, Niessing, Dierk, Sattler, Michael, Schlundt, Andreas, Bindereif, Albrecht
Publicado no Nat Commun (2019)

MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA

Por Groothuizen, Flora S, Winkler, Ines, Cristóvão, Michele, Fish, Alexander, Winterwerp, Herrie HK, Reumer, Annet, Marx, Andreas D, Hermans, Nicolaas, Nicholls, Robert A, Murshudov, Garib N, Lebbink, Joyce HG, Friedhoff, Peter, Sixma, Titia K
Publicado no eLife (2015)

The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair

Por Mardenborough, Yannicka S N, Nitsenko, Katerina, Laffeber, Charlie, Duboc, Camille, Sahin, Enes, Quessada-Vial, Audrey, Winterwerp, Herrie H K, Sixma, Titia K, Kanaar, Roland, Friedhoff, Peter, Strick, Terence R, Lebbink, Joyce H G
Publicado no Nucleic Acids Res (2019)

Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS

Por Monti, Maria Chiara, Cohen, Serge X., Fish, Alexander, Winterwerp, Herrie H. K., Barendregt, Arjan, Friedhoff, Peter, Perrakis, Anastassis, Heck, Albert J. R., Sixma, Titia K., van den Heuvel, Robert H. H., Lebbink, Joyce H. G.
Publicado em 2011