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3′-Phosphodiesterase and 3′→5′ Exonuclease Activities of Yeast Apn2 Protein and Requirement of These Activities for Repair of Oxidative DNA Damage

In Saccharomyces cerevisiae, the AP endonucleases encoded by the APN1 and APN2 genes provide alternate pathways for the removal of abasic sites. Oxidative DNA-damaging agents, such as H(2)O(2), produce DNA strand breaks which contain 3′-phosphate or 3′-phosphoglycolate termini. Such 3′ termini are i...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Unk, Ildiko, Haracska, Lajos, Prakash, Satya, Prakash, Louise
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2001
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC86711/
https://ncbi.nlm.nih.gov/pubmed/11238902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1656-1661.2001
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