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Yeast DNA Polymerase ζ Is an Efficient Extender of Primer Ends Opposite from 7,8-Dihydro-8-Oxoguanine and O(6)-Methylguanine

Genetic studies in Saccharomyces cerevisiae have indicated the requirement of DNA polymerase (Pol) ζ for mutagenesis induced by UV light and by other DNA damaging agents. However, on its own, Polζ is highly inefficient at replicating through DNA lesions; rather, it promotes their mutagenic bypass by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Haracska, Lajos, Prakash, Satya, Prakash, Louise
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC141155/
https://ncbi.nlm.nih.gov/pubmed/12556503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1453-1459.2003
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