Requirement of Watson-Crick Hydrogen Bonding for DNA Synthesis by Yeast DNA Polymerase η

Classical high-fidelity DNA polymerases discriminate between the correct and incorrect nucleotides by using geometric constraints imposed by the tight fit of the active site with the incipient base pair. Consequently, Watson-Crick (W-C) hydrogen bonding between the bases is not required for the effi...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Washington, M. Todd, Helquist, Sandra A., Kool, Eric T., Prakash, Louise, Prakash, Satya
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162216/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12832493/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.14.5107-5112.2003
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