Requirement of Watson-Crick Hydrogen Bonding for DNA Synthesis by Yeast DNA Polymerase η

Classical high-fidelity DNA polymerases discriminate between the correct and incorrect nucleotides by using geometric constraints imposed by the tight fit of the active site with the incipient base pair. Consequently, Watson-Crick (W-C) hydrogen bonding between the bases is not required for the effi...

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Detalhes bibliográficos
Main Authors: Washington, M. Todd, Helquist, Sandra A., Kool, Eric T., Prakash, Louise, Prakash, Satya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162216/
https://ncbi.nlm.nih.gov/pubmed/12832493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.14.5107-5112.2003
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