Requirement of DNA Polymerase η for Error-Free Bypass of UV-Induced CC and TC Photoproducts

The yeast RAD30-encoded DNA polymerase η (Polη) bypasses a cis-syn thymine-thymine dimer efficiently and accurately. Human DNA polymerase η functions similarly in the bypass of this lesion, and mutations in human Polη result in the cancer prone syndrome, the variant form of xeroderma pigmentosum. UV...

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Bibliografiset tiedot
Päätekijät: Yu, Sung-Lim, Johnson, Robert E., Prakash, Satya, Prakash, Louise
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2001
Aiheet:
DNA Dynamics and Chromosome Structure
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC88792/
https://ncbi.nlm.nih.gov/pubmed/11113193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.1.185-188.2001
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