Requirement of DNA Polymerase η for Error-Free Bypass of UV-Induced CC and TC Photoproducts

The yeast RAD30-encoded DNA polymerase η (Polη) bypasses a cis-syn thymine-thymine dimer efficiently and accurately. Human DNA polymerase η functions similarly in the bypass of this lesion, and mutations in human Polη result in the cancer prone syndrome, the variant form of xeroderma pigmentosum. UV...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Yu, Sung-Lim, Johnson, Robert E., Prakash, Satya, Prakash, Louise
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11113193/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.1.185-188.2001
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