Requirement of DNA Polymerase η for Error-Free Bypass of UV-Induced CC and TC Photoproducts
The yeast RAD30-encoded DNA polymerase η (Polη) bypasses a cis-syn thymine-thymine dimer efficiently and accurately. Human DNA polymerase η functions similarly in the bypass of this lesion, and mutations in human Polη result in the cancer prone syndrome, the variant form of xeroderma pigmentosum. UV...
Shranjeno v:
| izdano v: | Mol Cell Biol |
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| Principais autores: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2001
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11113193/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.1.185-188.2001 |
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