3′-Phosphodiesterase and 3′→5′ Exonuclease Activities of Yeast Apn2 Protein and Requirement of These Activities for Repair of Oxidative DNA Damage

In Saccharomyces cerevisiae, the AP endonucleases encoded by the APN1 and APN2 genes provide alternate pathways for the removal of abasic sites. Oxidative DNA-damaging agents, such as H(2)O(2), produce DNA strand breaks which contain 3′-phosphate or 3′-phosphoglycolate termini. Such 3′ termini are i...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Unk, Ildiko, Haracska, Lajos, Prakash, Satya, Prakash, Louise
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2001
Matèries:	DNA Dynamics and Chromosome Structure
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86711/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.5.1656-1661.2001
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