3′-Phosphodiesterase and 3′→5′ Exonuclease Activities of Yeast Apn2 Protein and Requirement of These Activities for Repair of Oxidative DNA Damage

In Saccharomyces cerevisiae, the AP endonucleases encoded by the APN1 and APN2 genes provide alternate pathways for the removal of abasic sites. Oxidative DNA-damaging agents, such as H(2)O(2), produce DNA strand breaks which contain 3′-phosphate or 3′-phosphoglycolate termini. Such 3′ termini are i...

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Bibliografske podrobnosti

izdano v:	Mol Cell Biol
Principais autores:	Unk, Ildiko, Haracska, Lajos, Prakash, Satya, Prakash, Louise
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 2001
Teme:	DNA Dynamics and Chromosome Structure
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86711/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.5.1656-1661.2001
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